NEW YORK (Reuters Health) Jan 15 - In nonpregnant women with asymptomatic bacterial vaginosis (BV), researchers observed a "modest, but impressively consistent" association between BV and colonization of the endometrium with BV-associated microorganisms.
However, in contrast to symptomatic BV, asymptomatic BV was not associated with plasma cell endometritis, report Dr. William W. Andrews and colleagues from the University of Alabama at Birmingham.
The researchers analyzed microbial cultures performed on endometrial specimens obtained from 769 women who experienced preterm delivery and were evaluated roughly 3 months' postpartum. Four hundred eight two women had endometrial specimens sufficient for histopathologic study as well.
Endometrial cultures were positive for at least 1 microorganisms in 83% of the women and plasma cell endometritis was seen in 39% of women, according to a report of the study in the American Journal of Obstetrics and Gynecology for December.
The frequency of positive endometrial cultures was only slightly higher among women with BV compared with women without BV and there was no association between BV and plasma cell endometritis, as mentioned.
What was "striking," according to Dr. Andrews and colleagues, was the "consistent and statistically significant association between BV ... and the likelihood of a positive endometrial culture for BV-associated bacteria defined and grouped in a variety of ways."
These observations, the researchers say, raise a number of questions. "Is the observed association between BV and upper tract colonization sufficient to explain the association between BV and spontaneous preterm birth or other adverse outcomes? Are these so-called BV-associated bacteria sufficiently virulent to cause spontaneous preterm birth when present only in modest increased frequency?"
"Does the observation that the association between BV and endometrial microbial colonization is only modest at best explain why the association between BV and preterm birth also is relatively modest, albeit a consistent observation?"
"More likely the relationships are simply more complex than our current understanding," Dr. Andrews and colleagues conclude.
Am J Obstet Gynecol 2006;195:1611-1616.
http://www.medscape.com/viewarticle/550803 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领 无症状细菌性阴道病患者子宫内膜通常发现细菌性阴道病相关细菌
来自伯明翰的阿拉巴马大学的William W. Andrews博士及其同事的报道指出，与有症状的BV相比，无症状性BV和浆细胞性子宫内膜炎并没有关联。
美国妇产科学杂志2006；195：1611-1616. 翻译的比较仓促，呵呵，不妥还望指教。 [标签:content1][标签:content2]
作者:admin@医学,生命科学 2011-09-17 06:33