主页 > 医学动态 >
【文摘发布】细针穿刺活检在直径小于1cm甲状腺
The Value of Fine-Needle Aspiration Biopsy in Subcentimeter Thyroid Nodules
Dilek Berker,1 Yusuf Aydin,1 Ihsan Ustun,1 Kamile Gul,2 Yasemin Tutuncu,1
Serhat Is¸ ık,1 Tuncay Delibasi,1 and Serdar Gule
Background: The need to perform fine-needle aspiration biopsy (TFNA on subcentimeter thyroid nodules is less clear than for larger nodules. We compared the ultrasonographic features of thyroid nodules less than and greater than one centimeter and correlated this information with the cytological results for TFNAB and the final histopathological diagnosis in selected patients.
Methods: We evaluated 520 thyroid nodules (247 subcentimeter [group 1], 273 supracentimeter [group 2]) in 426 patients. Ultrasonography-guided fine-needle aspiration biopsy was performed on all nodules. Surgery was recommended for patients with TFNAB results that were read as malignant or suspicious. The results of ultrasonography,
TFNAB, and histopathology were compared between the groups.
Results: Out of 426 patients, 337 had one nodule, 84 had two, and five had three. There was indeterminate cytology in 20 cases, 10 from each group. Inadequate cytology was obtained in 41=247 (16.6%) nodules in group 1 and 61=273 (22.3%) nodules in group 2, and the difference in rate was not significant ( p¼0.067). The malignancy
rate as determined by TFNAB was 4.9% in group 1 and 1.5% in group 2 ( p < 0.025). In patients who underwent surgery for thyroid nodules the malignancy rate was 6% in group 1 and 2.9% in group 2 ( p¼0.08). Hypoechoic pattern, microcalcification, and a long axis=short axis ratio (LA=SA) of < 1.5 were associated with malignancy in subcentimeter thyroid nodules (group 1), while only a hypoechoic pattern was associated
with malignancy in supracentimeter thyroid nodules (group 2).
Conclusions: The incidence of cancer in thyroid nodules < 1 cm does not appear to be lower than in larger nodules and may even be higher. Physicians should consider obtaining biopsy samples from subcentimeter hypoechoic nodules that contain microcalcification and have a relatively round shape (LA=SA < 1.5). 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 请两天有点忙。如果没人要认领，我再认领一次吧。
本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 The Value of Fine-Needle Aspiration Biopsy in Subcentimeter Thyroid Nodules
细针穿刺活检在亚中心甲状腺结节中的价值
Dilek Berker,1 Yusuf Aydin,1 Ihsan Ustun,1 Kamile Gul,2 Yasemin Tutuncu,1
Serhat Is¸ ık,1 Tuncay Delibasi,1 and Serdar Gule
作者：Dilek Berker,1 Yusuf Aydin,1 Ihsan Ustun,1 Kamile Gul,2 Yasemin Tutuncu,1
Serhat Is? ?k,1 Tuncay Delibasi,1 and Serdar Gule
Background: The need to perform fine-needle aspiration biopsy (TFNA on subcentimeter thyroid nodules is less clear than for larger nodules. We compared the ultrasonographic features of thyroid nodules less than and greater than one centimeter and correlated this information with the cytological results for TFNAB and the final histopathological diagnosis in selected patients.
背景：与较大甲状腺结节相比，细针穿刺活检用于小于1cm的甲状腺结节的必要性有待明确。在被纳入研究的病人中，我们通过超声特征比较了其小于和大于1cm的甲状腺结节的的细针穿刺活检结果和最终病检结果。
Methods: We evaluated 520 thyroid nodules (247 subcentimeter [group 1], 273 supracentimeter [group 2]) in 426 patients. Ultrasonography-guided fine-needle aspiration biopsy was performed on all nodules. Surgery was recommended for patients with TFNAB results that were read as malignant or suspicious. The results of ultrasonography,
TFNAB, and histopathology were compared between the groups.
方法：我们评估了426例患者的520个甲状腺结节（247个为小于1cm的——第一组，273个为大于1cm的——第二组）。所有的结节均在超声引导下完成细针穿刺活检。穿刺活检结果为恶性或可疑恶性者均被建议手术治疗。然后比较各组间超声、细针穿刺活检和手术切除后病检结果。
Results: Out of 426 patients, 337 had one nodule, 84 had two, and five had three. There was indeterminate cytology in 20 cases, 10 from each group. Inadequate cytology was obtained in 41=247 (16.6%) nodules in group 1 and 61=273 (22.3%) nodules in group 2, and the difference in rate was not significant ( p¼0.067). The malignancy
rate as determined by TFNAB was 4.9% in group 1 and 1.5% in group 2 ( p < 0.025). In patients who underwent surgery for thyroid nodules the malignancy rate was 6% in group 1 and 2.9% in group 2 ( p¼0.08). Hypoechoic pattern, microcalcification, and a long axis=short axis ratio (LA=SA) of < 1.5 were associated with malignancy in subcentimeter thyroid nodules (group 1), while only a hypoechoic pattern was associated
阅读本文的人还阅读：
作者:admin@医学,生命科学 2011-06-01 17:14
医学,生命科学网