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【文摘发布】BJOG(2007年5月)——腔镜辅助下的
腔镜辅助阴道子宫根治切除术治疗宫颈癌安全吗? 一项随访对照病例研究
DJ Morgan,aa Specialist Registrar, Stranmillis, Belfast, IrelandDJ Morgan, Specialist Registrar, 1 Penge Gardens, Stranmillis, Belfast BT9 5GA, Ireland. Email drdavidjmorgan@yahoo.co.uk DC Hunter,b b Royal Jubilee Maternity Service, Belfast, Ireland G McCracken,c c Belfast City Hospital, Belfast, Ireland HR McClelland,c c Belfast City Hospital, Belfast, Ireland JH Price,c c Belfast City Hospital, Belfast, Ireland SP Dobbsc c Belfast City Hospital, Belfast, Irelanda Specialist Registrar, Stranmillis, Belfast, Ireland b Royal Jubilee Maternity Service, Belfast, Ireland c Belfast City Hospital, Belfast, Ireland
DJ Morgan, Specialist Registrar, 1 Penge Gardens, Stranmillis, Belfast BT9 5GA, Ireland. Email drdavidjmorgan@yahoo.co.uk
DJ Morgan,aa,专科注册医师, Stranmillis,爱尔兰贝尔法斯特。DJ Morgan,专科注册医师,1 Penge 花园,Stranmillis,BT9 5GA,爱尔兰贝尔法斯特,电子邮件 drdavidjmorgan@yahoo.co.uk DC Hunter,b b 皇家Jubilee妇产科中心, 贝尔法斯特, 爱尔兰 G McCracken,c c爱尔兰贝尔法斯特市医院, HR McClelland,c c 爱尔兰贝尔法斯特市医院,JH Price,c c 爱尔兰贝尔法斯特市医院,SP Dobbsc c 爱尔兰贝尔法斯特市医院,注册专科医师,Stranmillis,爱尔兰贝尔法斯特, b Royal Jubilee Maternity Service,爱尔兰贝尔法斯特, c 贝尔法斯特 City Hospital, 爱尔兰贝尔法斯特,
DJ Morgan,专科注册医师,1 Penge 公园,Stranmillis,贝尔法斯特 BT9 5GA,爱尔兰,电子邮件 drdavidjmorgan@yahoo.co.uk
Abstract
Objective To compare a new surgical approach, laparoscopically assisted radical vaginal hysterectomy (LARVH) with open radical hysterectomy in women with cervical cancer. Can selected women benefit from the minimally invasive approach without compromising safety (recurrence rate) and morbidity (complications)?
摘要
目的:比较一种新的手术方法,用开放性子宫根治方法的腹腔镜辅助根治性子宫切除术LARVH)治疗子宫颈癌患者。经由该方法选择的妇女能受益于微创的办法,而无安全损害(复发率)和发病率(并发症)?
Design Retrospective case control study.
设计回顾性病例对照研究.
Setting A tertiary referral unit for gynaecological malignancies.
设置:为妇科肿瘤设立一个第三位的参照组
Population Thirty women undergoing LARVH were included and compared with 30 women undergoing open radical surgery. The control group was matched for age, body mass index and disease stage.
总体:有30例接受LARVH 的妇女和30例接受开放性根治手术的对照组妇女。对照组妇女在年龄,体重指数和疾病的阶段均匹配。
Methods Retrospective collection of data from patient files and follow up.
方法:对病人资料和随访信息的回顾性整理.
Main outcome measures Recurrence rate, complication rate, hospital stay, nodal counts, blood loss, operating time.
主要测量结果:疾病的复发率,并发症发病率,住院时间,淋巴结节计数,出血量,手术时间。
Results Recurrence rates were equal (6.7%). There was one death, in the LARVH group. Follow up was mean 31 months in the LARVH group and 30.9 months in the open group. Blood loss as measured by mean drop in haemoglobin was greater in the open group (2.03 versus 3.01 g/dl, P = 0.02). Transfusions were given in 40% of women in the open group and 16.7% in the LARVH group. Hospital stay was significantly less in the LARVH group (5.9 versus 7.8 nights, P = 0.003). Mean operating time was longer in the LARVH group (131 versus 187 minutes P = 0.0001). Mean nodal counts did not differ significantly (17.4 in open vs 14.8 in LARVH, P > 0.05). There were seven perioperative complications in the open group and four in the LARVH group. There have been two recurrences in each group (6.67%) at mean follow up of 31 (LARVH) and 30.9 (open) months.
结果:复发率分别相等为(6.7%)。在LARVH组有一例死亡。LARVH组和开放组随访平均时间为31个月和30.9个月。用血红蛋白平均下降值测量出血量,开放组数值较大 (2.03比3.01 g/d, p=0.02)。开放组中40%的妇女有输血,LARVH组为16.7%。住院时间,LARVH 组明显减少(5.9比7.8夜,p=0.003)。LARVH组平均手术时间较长(131比187分钟,p=0.0001)。 平均淋巴结节计数无明显差异(17.4开放组比14.8 LARVH 组,p>0.05)。共有七个并发症手术期并发症在公开组,LARVH组有四个。 已有两次复发每一组(6.67%),在平均随访31(LARVH组)和30.9(开放组)间,每组有两例复发(6.67%)
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作者:admin@医学,生命科学 2011-02-19 17:12
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