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【medical-news】男孩更易患哮喘
Published: Tuesday, 19-Aug-2008
According to researchers in the U.S. boys are more likely than girls to grow out of childhood asthma when they reach their teenage years.
The research on more than 1,000 children over an average of nine years, found that although boys were more likely to wheeze than girls, the symptoms were also more likely to disappear when boys reached adolescence.
Of the group 60% were boys, who, compared to girls, were diagnosed at a significantly younger age.
The researchers from the Brigham and Women's Hospital and Harvard Medical School, John Hopkins University, and the Washington University School of Medicine, say numerous potential confounding factors such as asthma severity, other allergies, family history and socio-environmental variables such as household smoking and pets were taken into account and the physical sexual maturity in both boys and girls were considered.
Dr. Kelan G. Tantisira and colleagues say they found that girls' airways were more likely to have a pronounced asthmatic response when exposed to provocative stimuli but both sexes were susceptible to a number of other factors that influenced airway responsiveness, such as a history of hay fever and allergies, and it could not be put down to one factor alone.
The study is expected to encourage further research into the processes involved in the development of asthma and the possible reasons why gender difference may influence its prognosis.
The researchers concluded that asthma is more severe in postpubertal females than postpubertal males males with asthma and suggest that hormonal mechanisms may play a part.
Experts agree and say sex hormones might play a role in the symptoms of asthma and its severity and that the research points to an unknown mechanism behind the development of asthma.
The study was funded by the National Heart, Lung and Blood Institute, the General Clinical Research Center, and the National Center for Research Resources. The study was published in the peer-reviewed medical journal: American Journal of Respiratory and Critical Care Medicine.
http://www.news-medical.net/?id=40784 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 Boys more likely to grow out of asthma
男孩更易戒除哮喘
According to researchers in the U.S. boys are more likely than girls to grow out of childhood asthma when they reach their teenage years.
美国研究表明，到了青春期后，男孩比女孩更容易戒除哮喘。
The research on more than 1,000 children over an average of nine years, found that although boys were more likely to wheeze than girls, the symptoms were also more likely to disappear when boys reached adolescence.
有超过1000名平均年龄为9岁的儿童参加了该项试验，研究结果显示，尽管男孩比女孩易患哮喘，但这些症状到了青春期后更可能消失。
Of the group 60% were boys, who, compared to girls, were diagnosed at a significantly younger age.
试验组60%是男孩，被确诊为少儿哮喘。
The researchers from the Brigham and Women's Hospital and Harvard Medical School, John Hopkins University, and the Washington University School of Medicine, say numerous potential confounding factors such as asthma severity, other allergies, family history and socio-environmental variables such as household smoking and pets were taken into account and the physical sexual maturity in both boys and girls were considered.
来自布赖海姆女子医院、哈弗医学院、霍普金斯大学和华盛顿大学医学院的研究者表示，应当充分考虑各种容易混淆的因素如哮喘的严重性、其他变态反应、家族史以及像吸烟和家养宠物这样的社会环境因素，另外，男孩和女孩的性成熟也应注意。
Dr. Kelan G. Tantisira and colleagues say they found that girls' airways were more likely to have a pronounced asthmatic response when exposed to provocative stimuli but both sexes were susceptible to a number of other factors that influenced airway responsiveness, such as a history of hay fever and allergies, and it could not be put down to one factor alone.
Kelan G. Tantisira博士和他的同事们说，当受到刺激时，女孩更容易诱发哮喘反应，对于多数影响气道的因素，比如花粉症和变态反应，无论男女都是易感人群，这不能归因于单独某一个因素。
The study is expected to encourage further research into the processes involved in the development of asthma and the possible reasons why gender difference may influence its prognosis.
至于哮喘病的进程以及性别差异影响预后的可能原因有待进一步研究。
The researchers concluded that asthma is more severe in postpubertal females than postpubertal males males with asthma and suggest that hormonal mechanisms may play a part.
研究者认为，青春期后女性哮喘比男性更严重，估计是荷尔蒙机制发挥着作用。
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作者:admin@医学,生命科学 2011-02-19 05:15
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