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【文摘发布】Olympus 细胞内镜检测结肠癌周围正常

Title: Detection of tissue abnormalities in normal mucosa surrounding colorectal cancer using an endocytoscopy system.

Author: Meroni E, Gatteschi B, Fasoli A, Munizzi F, Frascio F, Pugliese V, Truini M.

Resource: Endoscopy. 2007 Apr;39(4):369-70. Links

Abstract: The endocytoscopy system is a novel diagnostic technique that provides extremely high-magnification imaging of the gastrointestinal mucosa. We are currently using a prototype Olympus endocytoscope for clinical research in gastrointestinal tumors. In one surgical specimen obtained after resection of a cancer of the transverse colon, focal abnormalities of colonic glands were detected 7 cm away from the primary tumor, within macroscopically normal mucosa. Our finding, which was confirmed by histopathological examination, suggests the need for further clinical investigation to assess whether endocytoscopy is able to identify premalignant changes in apparently normal mucosa. This could potentially be useful for accurate evaluation before planning minimally invasive therapy.

PMID:17427076 本人已认领该文编译,48小时后若未提交译文,请其他战友自由认领 Title: Detection of tissue abnormalities in normal mucosa surrounding colorectal cancer using an endocytoscopy system.
题目:Olympus 细胞内镜检测结肠癌周围正常黏膜中的组织异常
Author: Meroni E, Gatteschi B, Fasoli A, Munizzi F, Frascio F, Pugliese V, Truini M.
作者:Meroni E, Gatteschi B, Fasoli A, Munizzi F, Frascio F, Pugliese V, Truini M.

Resource: Endoscopy. 2007 Apr;39(4):369-70. Links
来源:《内镜学》. 2007 Apr;39(4):369-70. Links
Abstract:摘要
The endocytoscopy system is a novel diagnostic technique that provides extremely high-magnification imaging of the gastrointestinal mucosa.
细胞内镜系统是一项新的诊断技术,能提供胃肠道粘膜的极高分辨率图像。

We are currently using a prototype Olympus endocytoscope for clinical research in gastrointestinal tumors.
我们目前在胃肠道肿瘤的临床研究中使用的是一台奥林巴斯细胞内镜样机。

In one surgical specimen obtained after resection of a cancer of the transverse colon, focal abnormalities of colonic glands were detected 7 cm away from the primary tumor, within macroscopically normal mucosa.
在外科手术切下来的横结肠癌标本上,离原发癌灶7厘米远、肉眼观察无异常的粘膜检测到结肠腺体的局灶性异常

Our finding, which was confirmed by histopathological examination, suggests the need for further clinical investigation to assess whether endocytoscopy is able to identify premalignant changes in apparently normal mucosa. This could potentially be useful for accurate evaluation before planning minimally invasive therapy.
我们的经组织病理学检查证实的发现表明有必要做进一步的临床研究以评价细胞内镜是否可以在看起来正常的粘膜发现癌前病变。这可能有助于在安排最低限度侵袭性治疗前做正确的评估。

PMID:17427076

编译:
共239字

【《内镜学》2007年4月报道】题目:Olympus 细胞内镜检测结肠癌周围正常黏膜中的组织异常(作者Meroni等)

细胞内镜系统是一项新的诊断技术,能提供胃肠道粘膜的极高分辨率图像。我们目前在胃肠道肿瘤的临床研究中使用的是一台奥林巴斯细胞内镜样机。在外科手术切下来的横结肠癌标本上,离原发癌灶7厘米远、肉眼观察无异常的粘膜检测到结肠腺体的局灶性异常。我们的经组织病理学检查证实的发现表明有必要做进一步的临床研究以评价细胞内镜是否可以在看起来正常的粘膜发现癌前病变。这可能有助于在安排最低限度侵袭性治疗前做正确的评估。
PMID:17427076 [标签:content1][标签:content2]

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作者:admin@医学,生命科学    2011-02-18 12:59
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