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【技术产业】世界首创：检测流感病毒的便携式
Portable Lab-on-Chip Detects Flu
检测流感病毒的便携式实验室芯片设备
Article Date: 26 Mar 2008 - 3:00 PDT
A joint venture between a microelectronics company and a medical diagnostics company has produced the world's first "lab-on-chip" portable device for detecting various types of flu, including bird flu, at the point of need.
通过微电子学公司和医疗诊断公司的一次冒险尝试，生产出世界首例便携式实验室芯片设备，可在需要的情况下，即时对包括禽流感病毒在内的多种流感病毒进行检测。
The launch of VereFlu, described as a "breakthrough molecular diagnostic test that can detect infection with high accuracy and sensitivity", was announced on Monday by its makers, STMicroelectronics of Switzerland and Veredus Laboratories of Singapore. The device was successfully trialled at the National University Hospital of Singapore.
该设备的生产者，瑞士STMicroelectronics和新加坡Veredus Laboratories在周一时宣布，VereFlu的上市是分子诊断检测技术的突破，对流感感染的检测具有高度的准确性和精密度。该设备已经在新加坡国立大学医院成功的完成实验。
Unlike other existing methods that take days and weeks, the new device can give genetic information about an infection within two hours. It is also portable, freeing the diagnostic process from the lab and allowing it to happen at the point of need.
现在使用的方法可能需要几天甚至几周的时间，而这种新型的设备可在几个小时内给出感染测定的基因信息，并且具有较好的便携性，可将诊断检测过程从实验室中解放出来，可以在任何需要的情况下进行即时检测。
VereFlu combines the In-Check lab-on-chip platform from STMicroelectronics, and the bio-application capability from Veredus.
VereFlu融合了STMicroelectronics的实验室芯片在线检测模式和Veredus的生物测定功能的优点。
The device integrates two powerful molecular biological applications to identify and differentiate, using a single test, human strains of Influenza virus types A and B, and the H5N1 strain of Avian Flu.
该装置整合了两个功能强大的分子生物测定设备用于测定过程中的鉴别和区分，通过一次测定就可以对人类所感染流感病毒的A型或B型或者H5N1禽流感进行确认和区分。
This portable "mini-lab" allows the diagnostician to analyze a patient sample like blood, serum and respiratory swabs, on a single disposable thumbnail-sized chip.
通过这种“便携式实验室”，诊断人员可以通过一个拇指大小的芯片，对患者的血液、血清以及呼吸道液体图片等样本进行检测。
As well as the obvious advantages of less cost and time, this method also reduces the risk of sample cross contamination that can occur in the conventional lab setting, said STMicroelectronics in a press statement.
STMicroelectronics在一项声明中认为，该方法除了上述节省成本和节约时间等优点外，还可以降低常规实验室操作中样品交叉污染的风险。
Head of Microbiology, Department of Laboratory Medicine, National University Hospital in Singapore, Associate Professor Raymond Lin said:
新加坡国立大学医院医疗实验系副教授、微生物学负责人Raymond Lin认为：
"We are pleased to report that our evaluation trials show the suitability of the VereFlu diagnostic application for field testing and deployment."
“根据我们进行的评价实验结果，我们非常高兴地发现VereFlu在场地检测和实时处理方面具有良好的适用性。”
He called the new device a "powerful weapon against future influenza pandemics".
他称这个新设备为“一种对付将来可能出现的流感病毒大流行的有力武器”。
Chief Executive Officer of Veredus Laboratories, Dr Rosemary Tan said:
Veredus Laboratories的首席执行官Rosemary Tan博士说：
VereFlu will enable healthcare professionals to effectively monitor mutations of flu viruses and quickly identify the main strain of the season."
“Vereflu将使医学专业人员更有效地监测流感病毒的变异，并能对不同季节流感的主要菌株进行快速地确认”。
This will increase the effectiveness of flu vaccination, she added, which should reduce the public health risks that arise when a new flu strain emerges.
她还补充说：“这将会增加流感疫苗的有效性， 进而在新的流感菌株出现时降低公共健康风险”。
Corporate VP and General Manager of ST's Computer Peripherals Group, Gian Luca Bertino said:
Corporate VP以及ST计算机外围小组总经理Gian Luca Bertino认为：
"The launch of VereFlu marks a substantial breakthrough in enabling rapid identification of the infectious agent to limit the spread of the disease and speed patients' treatment."
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作者:admin@医学,生命科学 2011-02-24 17:14
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