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【bio-news】女性基因组图谱有助于战胜疾病
本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 Female Genome Map May Help Fight Disease
Comprehensive Genetic Testing Could Reveal Blueprint For Most Common Diseases
NEW YORK, Oct. 24, 2006
女性基因组图谱有助于战胜疾病
综合性基因测试能够检测最常见疾病的蓝本
(CBS) Lee Coe is not a scientist. She’s a 67-year old retired social worker. But perhaps no one knows the importance of genetic research better than she does, CBS News medical correspondent Dr. Jon LaPook reports.
（哥伦比亚广播公司）
67岁的Lee Coe不是科学家，而是一个退休社工。但是，大概没有人比她更了解基因研究的重要性了。哥伦比亚广播公司医学新闻的记者Jon LaPook博士报道说。
Coe, who had a heart transplant last year, has a hereditary heart condition called cardiomyopathy, a disease that killed her mother and three of her brothers.
Coe去年进行了心脏移植。她患有遗传性心脏疾病—心肌病，这种疾病夺去了她的母亲和三位兄弟的生命。
"I feel extremely grateful because nobody in my family has lived this long," Coe says.
我非常感激，因为我的家族成员中没有人活得像我这样长，Coe说。
Now that the gene has been identified, it's changing the way her grandchildren, Ashlan and Conner, are growing up. They both carry the gene, too — but because they know it, their mother has been able to take precautions.
目前此病的致病基因已经明确了，她的孙子的命运也因此改变了，Ashlan和 Conner正在茁壮成长。虽然他们两个都携带有致病基因，但由于基因已知，因此他们的母亲采取了预防措施。
"I need to be able to guide them to music rather that football. More information is always a good thing," says Wendy Coe.
我所能够做的不是鼓励他们踢足球，而是指导他们学习音乐。这方面的信息多多益善。Wendy Coe说。
Personalized medicine through genetic testing is the way of the future.。
通过基因检测而进行个性化的治疗是未来的发展趋势。
"The goal here is not only about predicting disease, it's about how can we now treat them," says Dr. Paul Ridker, Eugene Braunwald Professor of Medicine at Brigham and Women's Hospital in Boston.
我们这样做的目的不仅仅是来预测疾病，而是目前如何对他们进行治疗。Paul Ridker博士说。他是波士顿Brigham妇产科医院的Eugene Braunwald医学教授。
This kind of personalized genetic testing goes well beyond a relatively rare form of heart disease. Scientists hope to reveal the genetic blueprints for the most common diseases, like breast cancer, osteoporosis and diabetes.
这种个性化的基因检测成功的应用于这种相对罕见类型的心脏病。科学家希望揭示一些更常见疾病的基因蓝本，像乳腺癌、骨质疏松症和糖尿病等。
It’s all being studied by scientists at Brigham and Women's. They've partnered with the federal government and Amgen to analyze the DNA of 28,000 healthy women, making it the largest genetic study of women's health to date.
Brigham妇产科医院的科学家们正在进行这项研究。他们与联邦政府和阿目金公司合作，对28000名健康妇女的DNA进行了分析。这是目前规模最大的关于女性健康的基因研究。
"These 28,000 women are really pioneers," Ridker says.
这28000名妇女才是真正的先锋，Ridker说。
Using blood samples taken from the women more than a decade ago, scientists are starting to run full genetic scans.
运用采自十年以前的妇女血样，科学家们开始进行全基因扫描。
"It's asking the question: Looking across your entire genetic basis, what's different between those women who actually develop breast cancer or heat attack and stroke and those women who don't," Ridker explains.
我们这样做正为了解答如下问题。研究那些患上乳腺癌、心脏病发作或者中风的女性与健康女性的遗传基础以发现二者有何不同？
While focused genetic research has helped people like the Coe family, the real promise lies with new, broader research, such as the Brigham and Women's study.
基因研究帮助了像Coe这样的家族，与此同时，更广阔的新研究像Brigham妇产科医院开展的这类，将会大显身手。
"They are agreeing to participate in something that hopefully will help them, but will more likely help their daughters," Ridker says.
那些愿意参加研究的人们将有希望从中获得帮助，也更会使他们的儿女收益，Ridker说。 怎么没有编译了 印象中你编译的稿件不少啊？！ 女性基因组图谱有助于战胜疾病
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作者:admin@医学,生命科学 2010-11-26 05:11
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