主页 > 医药科学 >
【medical-news】喝咖啡减少原发性睑痉挛风险
Last Updated: 2007-06-18 19:01:09 -0400 (Reuters Health)
NEW YORK (Reuters Health) - Daily coffee intake is inversely associated with the risk of primary late onset blepharospasm, a common type of late-onset dystonia, new research suggests.
By contrast, there was no significant evidence to support earlier reports of an anti-blepharospasm effect for cigarette smoking, according to a paper in the June 19th online issue of the Journal of Neurology, Neurosurgery, and Psychiatry.
The results stem from a case control study that included 166 patients with primary blepharospasm, 228 control patients with primary hemifacial spasm, and 187 population control subjects.
After adjusting for age, sex, disease duration, and other potential confounders, prior coffee intake was associated with a 56% to 63% reduced risk of blepharospasm, lead author Dr. Giovanni Defazio, from the University of Bari in Italy, and colleagues note. Moreover, as average daily coffee intake rose, the risk of dropped further.
Coffee intake was also tied to a delay in blepharospasm onset. For each additional cup consumed per day, the age of blepharospasm onset increased by 1.7 years.
As noted, cigarette smoking had no significant impact on blepharospasm risk and did not affect the age at disease onset.
Caffeine is the coffee ingredient most likely to be responsible for the effects seen, the report indicates. However, the authors note that this could not be examined in the study, which was based in Italy. A control group for this factor was unavailable, since relatively few people in this country drink decaffeinated coffee.
The researchers speculate that caffeine may protect against blepharospasm by blocking adenosine receptors, a mechanism that has also been proposed for its possible preventative effects on Parkinson's disease.
J Neurol Neurosurg Psychiatry 2007 online. 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 Coffee drinking tied to reduced risk of primary blepharospasm
喝咖啡减少原发性睑痉挛风险
Last Updated: 2007-06-18 19:01:09 -0400 (Reuters Health)
最新更新：2007-06-18 19:01:09 -0400 (路透社健康新闻)
NEW YORK (Reuters Health) - Daily coffee intake is inversely associated with the risk of primary late onset blepharospasm, a common type of late-onset dystonia, new research suggests.
路透社（健康）纽约报道——一项新的研究显示，每天饮用咖啡可逆转原发性睑痉挛的发作风险，一种常见迟发性肌张力障碍。
By contrast, there was no significant evidence to support earlier reports of an anti-blepharospasm effect for cigarette smoking, according to a paper in the June 19th online issue of the Journal of Neurology, Neurosurgery, and Psychiatry.
作为对照，依据神经病学、神经外科学与精神病学杂志6月19日的一篇论文，没有明显证据支持早先报道的吸烟的抗睑痉挛作用。
The results stem from a case control study that included 166 patients with primary blepharospasm, 228 control patients with primary hemifacial spasm, and 187 population control subjects.
结论来自于一项包含166例原发性睑痉挛、288例对照原发性半面部痉挛和187例正常人对照的专项对比研究。
After adjusting for age, sex, disease duration, and other potential confounders, prior coffee intake was associated with a 56% to 63% reduced risk of blepharospasm, lead author Dr. Giovanni Defazio, from the University of Bari in Italy, and colleagues note. Moreover, as average daily coffee intake rose, the risk of dropped further.
在调整年龄、性别、疾病时间和其他混杂因素后，预先摄入咖啡可减少睑痉挛风险56%-63%，第一作者意大利巴里大学的Giovanni Defazio博士和他的同事指出。而且，当日咖啡平均摄入量增加后，风险会减少更多。
Coffee intake was also tied to a delay in blepharospasm onset. For each additional cup consumed per day, the age of blepharospasm onset increased by 1.7 years.
摄入咖啡还可以延迟睑痉挛的发作。每天多喝一杯咖啡，睑痉挛发作的年龄增加1.7岁。
As noted, cigarette smoking had no significant impact on blepharospasm risk and did not affect the age at disease onset.
需要指出的是，吸烟没有显示可以影响睑痉挛风险，也不会影响睑痉挛发作的年龄。
Caffeine is the coffee ingredient most likely to be responsible for the effects seen, the report indicates. However, the authors note that this could not be examined in the study, which was based in Italy. A control group for this factor was unavailable, since relatively few people in this country drink decaffeinated coffee.
该报告指出，咖啡因是咖啡中最有可能对这种作用负责的活性成分。然而，作者也指出，这项在意大利进行的研究不能证实这点。因为在意大利很少有人饮用无咖啡因咖啡，无法获得该因素的对照研究组。
阅读本文的人还阅读：
作者:admin@医学,生命科学 2011-03-09 13:20
医学,生命科学网