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【medical-news】2型糖尿病使妇女更易患青光眼
BOSTON (July 10, 2006) -- A 20-year study of women in the Nurses' Health Study has shown that Type 2 diabetes is associated with primary open angle glaucoma (POAG), the most common form of glaucoma, accounting for about 60 to 70% of all glaucomas. The study is published in the July issue of the journal Ophthalmology.
Researchers at the Massachusetts Eye and Ear Infirmary, Brigham and Women's Hospital, Harvard School of Public Health and Harvard Medical School observed 76,3128 women who were enrolled in the Nurses' Health Study from 1980 to 2000. Eligible participants were at least 40 years old, did not have POAG at the beginning of the study, and reported receiving eye exams during follow-up. After controlling for age, race, hypertension, body mass index, physical activity, alcohol intake, smoking and family history of glaucoma, they found that type 2 diabetes was positively associated with POAG. However, the relation between type 2 diabetes and POAG did not increase with longer durations of type 2 diabetes.
"The study supports the notion that type 2 diabetes is associated with an increased risk of glaucoma," said Louis Pasquale, M.D., lead author of the study and co-director of the Glaucoma Service at the Massachusetts Eye and Ear Infirmary (MEEI) and an Assistant Professor of Ophthalmology at Harvard Medical School. "While obesity fuels the type 2 diabetes epidemic, it appears that factors unrelated to obesity contribute to the positive association between type 2 diabetes and glaucoma. We were surprised to find this. Our study had a large enough sample to allow us to focus on type 2 diabetes only and to study its relation to newly diagnosed POAG cases. We were also able to correct for other factors that could contribute to glaucoma. Our work suggests, but in now way proves, that factors other than lifestyle behavior contributing to insulin resistance could lead to elevated intraocular pressure and glaucoma."
According to the National Eye Institute, POAG affects more than 2 million individuals in the United States and is one of the leading causes of blindness. With the rapid aging of the U.S. population, the number of individuals affected by the disease will increase to more than 3 million by 2020.
The study suggests that people with type 2 diabetes should be screened for glaucoma. As of 2002, Medicare provides coverage for glaucoma screenings in beneficiaries with diabetes, helping to enhance access for this group who may be at risk for visual loss from POAG. 认领下来.明早交作业!呵呵 2型糖尿病增加妇女青光眼的患病风险
波士顿消息（2006年7月10日） 一项长达20年的妇女护理健康研究表明2型糖尿病联合最常见的青光眼类型-----原发性开放型青光眼约占所有青光眼患者的60%到70%。该项研究被发表在7月的眼科学杂志上。
来自于麻省眼耳医院、布里格姆妇女医院、哈佛大学公共卫生学院和哈佛大学医学院的研究人员在1998年—2000年期间观察了763128名在护理健康研究中注册的妇女。合格的观察对象要求大于40岁，在参加研究前未患有原发性开放型青光眼并且自愿接受眼睛测试的随访。通过控制年龄、种族、血压、体重指数、体力运动、酒精的摄入、吸烟和青光眼家族史等条件，他们发现2型糖尿病和原发性开放型青光眼间确实存在相关性，但是，二者之间相关度不因长期的2型糖尿病暴露而增加。
“这项研究支持这样一个观点，2型糖尿病是青光眼的一个高危因素。”该项研究的先驱者麻省眼耳医院青光眼中心副主任，哈佛医学院眼科学副教授 Louis Pasquale博士指出。“尽管肥胖导致2型糖尿病的流行，但是与肥胖无关的因素同样促使2型糖尿病和青光眼间存在确切的关系。这令我们感到非常惊讶。我们的研究有足够的样本允许我们单独关注2型糖尿病并研究其与新确诊的原发性开放型青光眼病例的关系。我们还可以校正其他导致青光眼的因素。我们的工作提示除生活方式以外的其他导致胰岛素抵抗因素能够增加眼内压和导致青光眼。”
根据国立眼科研究所统计，在美国有超过二百万的原发性开放型青光眼患者，它已成为导致失明的主要原因。随着美国人口的迅速老龄化，到2020年原发性开放型青光眼患者将超过三百万。
该项研究提示2型糖尿病患者有必要进行青光眼的普查筛选。从2002年起，医疗保险已经覆盖到这一领域，使患有糖尿病的受益人参加青光眼的普查筛选，这一措施有助于降低该人群因原发性开放型青光眼而导致失明的风险。 我觉得lanlan有几处翻译得不是太妥当，如下括号数字所示。不知意下如何？
2型糖尿病增加妇女青光眼的患病风险
波士顿消息（2006年7月10日） 一项长达20年的妇女护理健康研究表明(1)2型糖尿病联合最常见的青光眼类型-----原发性开放型青光眼约占所有青光眼患者的60%到70%。该项研究被发表在7月的眼科学杂志上。
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作者:admin@医学,生命科学 2011-03-28 17:11
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