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【medical-news】高钙饮食增加前列腺癌患病风险
High calcium levels may raise prostate cancer risk
Tue Jun 5, 2007 4:43PM EDT
NEW YORK (Reuters Health) - The results of a study published in the International Journal of Cancer indicate there is an association between dietary calcium and the risk of prostate cancer.
It has been suggested that increased consumption of calcium and dairy products raises the risk of prostate cancer, report Dr. Panagiota N. Mitrou, of the National Cancer Institute, Rockville, Maryland, and colleagues.
To further investigate, the researchers used data from the Alpha-Tocopherol, Beta-Carotene (ATBC) Cancer Prevention Study to examine dietary levels of calcium and dairy products and their relationship with prostate cancer risk. The ATBC study included 29,133 Finnish male smokers between the ages of 50 and 69 years old at study enrollment who completed a 276-item food questionnaire to assess the content of their diet.
During 17 years of follow-up, the team identified 1,267 cases of prostate cancer. A total of 27,028 participants had complete data available and were included in the final analysis.
"We found a strong, graded, positive association between calcium intake and total prostate cancer risk," the researchers report. After adjusting the data for potentially influential variables, the risk of prostate cancer was 63 percent greater for subjects who consumed 2,000 milligrams per day or more of calcium compared with those who consumed less than 1,000 milligrams per day, a statistically significant difference.
A positive association was also observed between total dairy intake and prostate cancer risk, but this disappeared after eliminating the influence of calcium. In other words, the positive association between dairy fat and prostate cancer disappeared after calcium was eliminated, the authors note.
They point out that prostate specific antigen (PSA) screening, a marker for prostate cancer, has not been widely adopted in Finland. "Therefore, a large proportion of cases in our study were detected as a result of clinical symptoms," Mitrou's team explains. "This lessens the possibility that our results are influenced by detection bias."
SOURCE: International Journal of Cancer, June 2007. 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 本人已认领该文编译，12小时后若未提交译文，请其他战友自由认领。 http://www.reuters.com/article/healthNews/idUSKRA57460720070605
High calcium levels may raise prostate cancer risk
Tue Jun 5, 2007 4:43PM EDT
高钙饮食增加前列腺癌患病风险
NEW YORK (Reuters Health) - The results of a study published in the International Journal of Cancer indicate there is an association between dietary calcium and the risk of prostate cancer.
纽约（路透社健康新闻部）——发表在《国际癌症杂志》上的一项研究结果显示，饮食中的钙含量与前列腺癌患病风险具有相关性。
It has been suggested that increased consumption of calcium and dairy products raises the risk of prostate cancer, report Dr., of the National Cancer Institute, Rockville, Maryland, and colleagues.
据美国国立癌症研究所的Panagiota N. Mitrou博士及其同事报道，业已表明，增加钙和乳制品的摄入量可增加前列腺癌患病风险。
To further investigate, the researchers used data from the Alpha-Tocopherol, Beta-Carotene (ATBC) Cancer Prevention Study to examine dietary levels of calcium and dairy products and their relationship with prostate cancer risk. The ATBC study included 29,133 Finnish male smokers between the ages of 50 and 69 years old at study enrollment who completed a 276-item food questionnaire to assess the content of their diet.
为了进一步的研究，研究人员对“α生育酚和β-胡萝卜素（ATBC）预防癌症研究”的资料进行分析，以考察饮食中的钙含量和乳制品以及它们与前列腺癌患病风险的关系。ATBC研究项目共纳入29133名芬兰男性吸烟人群，其年龄介于50-69岁之间，在入组时他们完成了276项有关食物的问卷调查以分析其饮食结构。
During 17 years of follow-up, the team identified 1,267 cases of prostate cancer. A total of 27,028 participants had complete data available and were included in the final analysis.
在此后的17年随访期间，该研究小组确诊了1267例前列腺癌症患者，共计27028名参与者的资料完整可用，并参与了最后分析。
"We found a strong, graded, positive association between calcium intake and total prostate cancer risk," the researchers report. After adjusting the data for potentially influential variables, the risk of prostate cancer was 63 percent greater for subjects who consumed 2,000 milligrams per day or more of calcium compared with those who consumed less than 1,000 milligrams per day, a statistically significant difference.
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作者:admin@医学,生命科学 2011-03-28 05:11
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