主页 > 医学新闻 >
【medical-news】大麻治疗骨质疏松症的潜在价值
原文链接： http://www.medicalnewstoday.com/articles/160709.php
Potential Value Of Cannabis In The Fight Against Osteoporosis
Scientists investigating the effects of cannabis on bone health have found that its impact varies dramatically with age.
The study has found that although cannabis could reduce bone strength in young people, it may protect against osteoporosis, a weakening of the bones, in later life.
The team at the University of Edinburgh has shown that a molecule found naturally in the body, which can be activated by cannabis - called the type 1 cannabinoid receptor (CB1) - is key to the development of osteoporosis.
It is known that when CB1 comes into contact with cannabis it has an impact on bone regeneration, but until now it was not clear whether the drug had a positive or negative effect.
Researchers, funded by the Arthritis Research Campaign, investigated this by studying mice that lacked the CB1 receptor. The scientists then used compounds - similar to those in cannabis - that activated the CB1 receptor. They found that compounds increased the rate at which bone tissue was destroyed in the young.
The study also showed, however, that the same compounds decreased bone loss in older mice and prevented the accumulation of fat in the bones, which is known to occur in humans with osteoporosis. The results are published in Cell Metabolism.
Osteoporosis affects up to 30 per cent of women and 12 per cent of men at some point in life.
Stuart Ralston, the Arthritis Research Campaign Professor of Rheumatology at the University of Edinburgh, who led the study, said: "This is an exciting step forward, but we must recognise that these are early results and more tests are needed on the effects of cannabis in humans to determine how the effects differ with age in people.
"We plan to conduct further trials soon and hope the results will help to deliver new treatments that will be of ." 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 大麻治疗骨质疏松症的潜在价值
原文链接： http://www.medicalnewstoday.com/articles/160709.php
Potential Value Of Cannabis In The Fight Against Osteoporosis
大麻治疗骨质疏松症的潜在价值
Scientists investigating the effects of cannabis on bone health have found that its impact varies dramatically with age.
研究大麻对骨健康影响的科学家发现它的作用随年龄不同差异变化很大。
The study has found that although cannabis could reduce bone strength in young people, it may protect against osteoporosis, a weakening of the bones, in later life.
研究发现尽管大麻能减少年轻人的骨质强度，但在日后却可能防止骨质变弱的骨质疏松。
The team at the University of Edinburgh has shown that a molecule found naturally in the body, which can be activated by cannabis - called the type 1 cannabinoid receptor (CB1) - is key to the development of osteoporosis.
爱丁堡大学研究小组指出，一种体内可以被大麻激活的天然分子 --- 称为 1 型大麻受体（CB1） - 是骨质疏松发生的关键。
It is known that when CB1 comes into contact with cannabis it has an impact on bone regeneration, but until now it was not clear whether the drug had a positive or negative effect.
已经知道 CB1 和大麻接触后将对骨再生产生影响，但尚未清楚它是正效应还是负效应。
Researchers, funded by the Arthritis Research Campaign, investigated this by studying mice that lacked the CB1 receptor. The scientists then used compounds - similar to those in cannabis - that activated the CB1 receptor. They found that compounds increased the rate at which bone tissue was destroyed in the young.
由关节炎研究运动资助的研究人员们，通过对缺乏 CB1 受体的小鼠的学习，深入研究了这个现象。然后科学家们利用了与大麻类似的能激活 CB1 受体的物质。他们发现了该类似化合物增加了年轻人骨组织破坏的速率。
The study also showed, however, that the same compounds decreased bone loss in older mice and prevented the accumulation of fat in the bones, which is known to occur in humans with osteoporosis. The results are published in Cell Metabolism.
该研究还显示了同一化合物减少了老年小鼠的骨丢失，井防止了已知会在骨质疏松患者身上发生的骨中脂肪堆积。该结果已发表在《Cell Metabolism》。
Osteoporosis affects up to 30 per cent of women and 12 per cent of men at some point in life.
骨质疏松困扰了一生的某个阶段的最多达到 30％ 的妇女和 12％ 男人。
Stuart Ralston, the Arthritis Research Campaign Professor of Rheumatology at the University of Edinburgh, who led the study, said: "This is an exciting step forward, but we must recognise that these are early results and more tests are needed on the effects of cannabis in humans to determine how the effects differ with age in people.
阅读本文的人还阅读：
作者:admin@医学,生命科学 2010-12-24 17:30
医学,生命科学网