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【科普】糖果也能防蛀？
CHICAGO (Reuters) - Most children are told to stay away from chewy candies to keep their teeth cavity-free, but children in Venezuela who ate a special cavity-fighting candy had 62 percent fewer cavities than those who brushed their teeth regularly, researchers said on Tuesday.
Children in the study were testing the effectiveness of BasicMints, an experimental fluoride-free treatment designed to mimic a component in human saliva that neutralizes acids in the mouth that can erode tooth enamel.
Researchers at Stony Brook University School of Dental Medicine, who developed the active compound in the mints known as CaviStat, tested them in 200 children in Venezuela aged 10 1/2 to 11 who were getting their adult molars but still had some baby teeth left.
Half the children in the study took two of the medicated mints in the morning after brushing with a fluoride toothpaste. They followed the same routine at night. The other half brushed normally twice daily with fluoride toothpaste and took plain sugarless mints.
After 12 months, children who took the cavity-fighting mints had 61.7 percent fewer cavities than the placebo group.
The soft mints are designed to be dissolved and chewed into the biting surfaces of the back teeth, where about 90 percent of cavities in children occur.
"Unlike regular candies, we want this product to be stuck in the teeth," said Mitchell Goldberg, president of Ortek Therapeutics Inc, a privately held company in Roslyn Heights, New York, that licensed the technology from Stony Brook.
Goldberg said in a telephone interview that unlike sugarless gum, which fights cavities by temporarily increasing the flow of saliva in the mouth, the mints actively neutralize acids that cause cavities.
He said the company plans to seek U.S. Food and Drug Administration approval to begin testing the product in the United States by year end. It may take several years of testing before it wins U.S. marketing approval.
The study was published in the March issue of the Journal of Clinical Dentistry.
screen.width-333)this.width=screen.width-333" width=128 height=160 title="Click to view full 18302.gif (128 X 160)" border=0 align=absmiddle> 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 Cavity-fighting candy helped cut tooth decay: study
[科普] 糖果也能防蛀
CHICAGO (Reuters) - Most children are told to stay away from chewy candies to keep their teeth cavity-free, but children in Venezuela who ate a special cavity-fighting candy had 62 percent fewer cavities than those who brushed their teeth regularly, researchers said on Tuesday.
芝加哥(路透社) — 在星期二的报道中说，为了预防蛀牙大多数儿童被告之远离糖果，但委内瑞拉的儿童吃一种特殊的糖果来预防蛀牙，比那些有规律刷牙的儿童的蛀牙还少62%。
Children in the study were testing the effectiveness of BasicMints, an experimental fluoride-free treatment designed to mimic a component in human saliva that neutralizes acids in the mouth that can erode tooth enamel.
为了研究试验中的儿童使用碱性薄荷糖的效果，用一种无氟治疗来模拟口腔唾液中能抑制引起牙釉质腐蚀的酸性物质的实验。
Researchers at Stony Brook University School of Dental Medicine, who developed the active compound in the mints known as CaviStat, tested them in 200 children in Venezuela aged 10 1/2 to 11 who were getting their adult molars but still had some baby teeth left.
立石溪大学的牙科研究员，研究了众所周知的薄荷中的活性成分CaviStat，测试了200个年龄在10岁半到11岁正在长恒齿的但还有一些在换牙的委内瑞拉儿童。
Half the children in the study took two of the medicated mints in the morning after brushing with a fluoride toothpaste. They followed the same routine at night. The other half brushed normally twice daily with fluoride toothpaste and took plain sugarless mints.
参加试验的一半儿童，在早晨用氟化物牙膏刷牙并且吃两种含药的薄荷糖。他们晚上也是同样的程序。另一半儿童在一天中用氟化物牙膏普通刷牙两次并且吃单纯的无糖薄荷糖。
After 12 months, children who took the cavity-fighting mints had 61.7 percent fewer cavities than the placebo group.
12个月以后，服用防蛀薄荷糖的儿童的蛀牙比服用安慰剂的少了61.7%。
The soft mints are designed to be dissolved and chewed into the biting surfaces of the back teeth, where about 90 percent of cavities in children occur.
设计这种薄荷糖成一种柔软的易于溶解的、能够嚼进坏齿的蚀痛表面内，大约90%的儿童达到了防蛀。
"Unlike regular candies, we want this product to be stuck in the teeth," said Mitchell Goldberg, president of Ortek Therapeutics Inc, a privately held company in Roslyn Heights, New York, that licensed the technology from Stony Brook.
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作者:admin@医学,生命科学 2010-11-21 17:11
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