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《Nature Medicine》 2004 wrap up

《Nature Medicine》 在最近一期( December 2004, Volume. 10. No. 12 ) 发布了名为 《The Year that was -- 2004 wrap up》的医学2004年大事记略 ——从新闻、人物、科技进展等多方面对2004年的医学进行了一个总结。
全文链接:
http://www.dxy.cn/bbs/user/download/2263101/nm1204-1273.pdf 欢迎进一步整理其间的新闻、人物、科技进展 今后若上传全文请到:
进展跟踪】【review】专用空间
http://www.dxy.cn/bbs/post/view?bid=36&id=2020518&sty=1&tpg=1&age=0
附件不会删除,【友情空间赞助点】的附件是不定期删除的。
谢谢! 谢谢biodna主任的帮助和提醒. 新闻方面:
1.禽流感病毒H5N1亚型在亚洲的流行,感染动物之广,使得各国政府不得不杀死200多万只家禽,影响了当地经济的发展,并导致32人死亡(仅11月份就有17例).
尽管去年的SARS爆发对疾病监控工作有所加强,但是尚存差距.从H5N1的爆发到见诸于文字报道,中国整整晚了7个月. 由于两个主要实验室发生污染,美国在疫苗供应方面也一度出现问题.
http://www.dxy.cn/bbs/user/download/2267371/430955.pdf

2.关于文献共享问题的讨论,政府与生物专家各执一词.相关报道如下:
In Britain, an inquiry by the House of Commons Science and Technology Committee concluded in July that open access seems viable but requires further experimentation. The committee advised the government to require UK-based authors to publish articles on their institutions' websites, but the government largely rejected the advice on 8 November. In August, 25 Nobel laureates signed a letter calling on the US government to provide public access to government-funded research. As a result, the US National Institutes of Health in September invited comments on a proposal to make the results of all federally funded research freely available shortly after publication. And in October, the German government gave 6.1 million to the Max Planck Society to develop an open-access system for publications from the society's institutes.

Meanwhile, 48 biomedical societies united to oppose open access. On 16 March, they launched a series of Principles for Free Access to Science, which backs open access but reserves the right of publishers to charge for several months after publication. Society editors argued that it would be impossible to generate income for other society activities if they only raised money through payments from authors.

3.关于生殖生物学方面,2月份韩国报道已成功克隆了人类胚胎;3月份,有关组织宣布猴子的克隆成功(冷冻卵组织移植到腹腔);仅仅数月之后,经化疗后的何杰氏淋巴瘤存活的母亲,通过卵细胞移植,正常妊赈生下一的女婴( Lancet 364 , 1405–1410; 2004). 雌性鼠卵细胞克隆以及由干细胞来源的卵细胞研究也取得一定成就.
http://www.dxy.cn/bbs/user/download/2267542/428137.pdf
http://www.dxy.cn/bbs/user/download/2267597/nature02402.pdf
http://www.dxy.cn/bbs/user/download/2267612/nature02316.pdf

4.药品临床实验方面,欧洲加强了相关法律,明确了制药企业的法律责任,保护了病人的相关利益.但是学术研究学者们对此颇有微词.......
On 1 May, the European Union launched its clinical trials directive to normalize and improve trials. The new regulations are intended to establish the legal obligations of trial sponsors and ensure greater patient protection. But some academic researchers have protested the directive since its announcement in 2001, saying it will be difficult for them to meet the regulatory requirements and cost. In March, the UK unveiled the National Clinical Research Network to centralize funding and regulation of clinical trials. And in April, the World Health Organization, in conjunction with Current Controlled Trials, part of an independent publishing group, announced an online registry to improve tracking and comparison of randomized trials worldwide. The issue intensified when, responding to concerns about the selective reporting of trial data, the editors of 11 leading medical journals announced in September that registering trials in a free, searchable public database would be a prerequisite for considering manuscripts for publication in their journals. In October, the US Senate and Congress introduced legislation seeking mandatory registration of clinical trials.

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2004诺贝尔奖拉开序幕 今

作者:admin@医学,生命科学    2010-09-28 05:11
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