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【medical-news】维生素D可能有助于延缓乳腺癌病程
Mon Oct 16, 2006 7:06pm ET
By Patricia Reaney
LONDON (Reuters) - High levels of vitamin D may help slow the progression of breast cancer, researchers suggested on Tuesday.
In a small study of women with the illness they found that patients with early breast cancer had higher levels of the vitamin than those with more advanced disease.
"Vitamin D levels are lower in women with advanced breast cancer than in early breast cancer," said Dr Carlo Palmieri, of Imperial College London.
"It lends support to the idea that vitamin D has a role in the progression of breast cancer," he told Reuters.
The researchers measured the amount of vitamin D in blood samples from 279 women with breast cancer. In 204 women, the disease was in its early stages. It was more advanced in the other 75.
"We know from previous studies that breast cancer incidence is higher in women who live in higher latitudes and have less sun exposure," said Palmieri.
Vitamin D, the so-called sunshine vitamin, is found in fortified milk and dairy products, cod liver oil and some fatty fish.
The body produces vitamin D in the skin when it is exposed to sunlight. Laboratory tests have also shown that vitamin D can stop cancer cells from dividing.
Breast cancer is the most common cancer in women, with more than a million cases detected worldwide each year, according to the International Agency for Research on Cancer (IARC) in Lyon, France. The earlier the cancer is detected and treated, the greater the chances of survival.
Although the scientists do not know whether the low levels of vitamin D are a cause or a consequence of the cancer, their findings and the results of other studies suggest that low levels of vitamin D may be involved in the progression of early breast cancer to more advanced stages.
"The next thing in this research is to try and understand the potential causes and mechanisms underlying these differences and the precise consequences at a molecular level," said Palmieri, who reported the finding in the Journal of Clinical Pathology.
"We also need to look at the potential clinical implications of monitoring and maintaining high circulating vitamin D levels in breast cancer patients," he added in a statement.
Breast cancer is treated with surgery and radiotherapy, chemotherapy and hormone treatment, or a combination of them, depending on the cancer and stage of the illness.
Factors which can increase a woman's risk of breast cancer include having a mother or close relative with the disease, inherited mutations in the BRCA1 or BRCA2 genes, an early puberty, late menopause and not having any children.
http://today.reuters.com/news/articlenews.aspx?type=healthNews&storyID=2006-10-16T230631Z_01_L16540313_RTRUKOC_0_US-CANCER-BREAST.xml&WTmodLoc=HealthNewsHome_C1_%5bFeed%5d-2 认领这篇 Vitamin D may help slow breast cancer –study
维生素D可能有助于减缓乳腺癌病程—研究
By Patricia Reaney
LONDON (Reuters) - High levels of vitamin D may help slow the progression of breast cancer, researchers suggested on Tuesday.
伦敦（路透社）----高水平维生素D可能有助于延缓乳腺癌的演进，研究人员周二提示。
In a small study of women with the illness they found that patients with early breast cancer had higher levels of the vitamin than those with more advanced disease.
在罹患乳腺癌的妇女中的一个小型研究中他们发现，早期乳腺癌患者体内维生素水平晚期患者的高。
"Vitamin D levels are lower in women with advanced breast cancer than in early breast cancer," said Dr Carlo Palmieri, of Imperial College London.
“晚期乳腺癌患者体内维生素D水平低于早期乳腺癌（患者体内）维生素D水平。”伦敦帝国大学Carlo Palmieri博士说。
"It lends support to the idea that vitamin D has a role in the progression of breast cancer," he told Reuters.
“这对维生素D在乳腺癌演进中起作用提供了支持。”他告诉路透社。
The researchers measured the amount of vitamin D in blood samples from 279 women with breast cancer. In 204 women, the disease was in its early stages. It was more advanced in the other 75.
研究人员测量了279位乳腺癌患者血样中的维生素D含量。其中204位癌症处于早期。另外75位的乳腺癌恶性程度更高。
"We know from previous studies that breast cancer incidence is higher in women who live in higher latitudes and have less sun exposure," said Palmieri.
“我们在先前的研究中了解到乳腺癌的发病率在高纬度和缺少日晒的地区较高。”Palmieri说。
Vitamin D, the so-called sunshine vitamin, is found in fortified milk and dairy products, cod liver oil and some fatty fish.
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作者:admin@医学,生命科学 2010-11-14 05:11
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