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【文摘发布】2003年美国乳腺癌发病率下降

RESOURCE: NEJM.Volume 356:1670-1674 April 19, 2007 Number 16

TITLE: The Decrease in Breast-Cancer Incidence in 2003 in the United States

AUTHOR: Peter M. Ravdin, Ph.D., M.D., Kathleen A. Cronin, Ph.D., Nadia Howlader, M.S., Christine D. Berg, M.D., Rowan T. Chlebowski, M.D., Ph.D., Eric J. Feuer, Ph.D., Brenda K. Edwards, Ph.D., and Donald A. Berry, Ph.D.

Abstract

An initial analysis of data from the National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) registries shows that the age-adjusted incidence rate of breast cancer in women in the United States fell sharply (by 6.7%) in 2003, as compared with the rate in 2002. Data from 2004 showed a leveling off relative to the 2003 rate, with little additional decrease. Regression analysis showed that the decrease began in mid-2002 and had begun to level off by mid-2003. A comparison of incidence rates in 2001 with those in 2004 (omitting the years in which the incidence was changing) showed that the decrease in annual age-adjusted incidence was 8.6% (95% confidence interval [CI], 6.8 to 10.4). The decrease was evident only in women who were 50 years of age or older and was more evident in cancers that were estrogen-receptor–positive than in those that were estrogen-receptor–negative. The decrease in breast-cancer incidence seems to be temporally related to the first report of the Women's Health Initiative and the ensuing drop in the use of hormone-replacement therapy among postmenopausal women in the United States. The contributions of other causes to the change in incidence seem less likely to have played a major role but have not been excluded.


Figure 1. Annual Incidence of Female Breast Cancer (1975–2004).Data are from nine of the NCI's SEER registries. SEER sites include San Francisco, Connecticut, Detroit (metropolitan area), Hawaii, Iowa, New Mexico, Seattle–Puget Sound, Utah, and Atlanta (metropolitan area). 1、
An initial analysis of data from the National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) registries shows that the age-adjusted incidence rate of breast cancer in women in the United States fell sharply (by 6.7%) in 2003, as compared with the rate in 2002. Data from 2004 showed a leveling off relative to the 2003 rate, with little additional decrease.
来源于国家癌症研究院,流行病学调查结果的最初的分析数据证实,2003年龄差异修正后的美国女性乳癌的发病率同2002年相比陡降6.7个百分点。2004年基本和2003年持平。 Post is deleted
xunl9 wrote:
这个里面的那个完全是我自己翻译的,我并不认为我是错的。而且和漂亮瓶的交流中,我们也探讨了这一点,英语翻译中有直译和意译两种方式,我们取其主要内容。英文不是我们的母语,大家只是根据个人的理解,翻译后的东西是大家共同认定的东西就可以的,不知道为什么不能加分!
附 漂亮瓶给我的悄悄话,不知道为什么用悄悄话,对了就对了,错了就错了,不好意思说?

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作者:admin@医学,生命科学    2010-11-09 05:11
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