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【medical-news】老年人的视网膜血管状态可以反应
2/13/2007
By: Reuters Health
http://www.auntminnie.com/index.asp?Sec=sup&Sub=mri&Pag=dis&ItemId=74596
NEW YORK (Reuters Health), Feb 12 - There are associations between findings on cranial magnetic resonance imaging (MRI) and retinal photography in the elderly, as has been already been established for small vessel disease in younger subjects, according to researchers.
Lead investigator Dr. W. T. Longstreth Jr. told Reuters Health, "Evidence of small vessel disease in the retina increases the likelihood of finding it in the brain." Nevertheless, he added, "associations were less prominent in this elderly population than have been described in middle-aged people."
Dr. Longstreth of the University of Washington, Seattle, and colleagues studied MRI findings and retinal photographs from 1,707 subjects age 65 years or more who had taken part in a cardiovascular health study. They report the results in the January issue of the American Journal of Epidemiology.
After controlling for age and gender, the team found associations between a smaller ratio of retinal arterioles and venules with MRI findings, including prevalent infarcts, worsening white matter grade, and incident infarct. Arteriovenous nicking was also associated with prevalent and incident infarcts.
The researchers conclude that these and other findings "support the importance of small vessel disease as a cause of brain injury and subsequent and subsequent disability, which may have implications for prevention and treatment."
Last Updated: 2007-02-12 15:46:52 -0400 (Reuters Health)
Am J Epidemiol 2007;165:78-84. 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。
老年人的视网膜血管状态可以反应脑内小血管的情况
NEW YORK (Reuters Health), Feb 12 - There are associations between findings on cranial magnetic resonance imaging (MRI) and retinal photography in the elderly, as has been already been established for small vessel disease in younger subjects, according to researchers.
纽约 路透社健康专栏2月12日 — 据研究人员报道，在老年人的颅内磁共振成像和视网膜成像存在某些关联，即较为年轻的受试者存在小血管疾病已经确认。
Lead investigator Dr. W. T. Longstreth Jr. told Reuters Health, "Evidence of small vessel disease in the retina increases the likelihood of finding it in the brain." Nevertheless, he added, "associations were less prominent in this elderly population than have been described in middle-aged people."
首席研究员 W. T. Longstreth 医师向路透社健康专栏透露，“视网膜的小血管疾病增加患病风险的可能性的证据已在脑部发现，”另外他补充道“在已经报道的中年人群中二者的关联性要比中年以上人群更为显著。”
Dr. Longstreth of the University of Washington, Seattle, and colleagues studied MRI findings and retinal photographs from 1,707 subjects age 65 years or more who had taken part in a cardiovascular health study. They report the results in the January issue of the American Journal of Epidemiology.
西雅图华盛顿大学的Longstreth医师及其同事对来自1707名65岁及以上年龄的受试者的核磁共振结果和视网膜成像进行了研究，这些受试者之前曾参与心血管的健康研究。他们的研究结果发表在一月份的美国流行病学杂志。
After controlling for age and gender, the team found associations between a smaller ratio of retinal arterioles and venules with MRI findings, including prevalent infarcts, worsening white matter grade, and incident infarct. Arteriovenous nicking was also associated with prevalent and incident infarcts.
在对年龄和性别进行控制后，研究小组在磁共振结果中发现较小比率视网膜小动脉和小静脉之间的联系，包括普遍的梗塞，恶化的白质程度，以及偶发的梗塞。动静脉局部狭窄也同普遍和偶发的梗塞相联系。
The researchers conclude that these and other findings "support the importance of small vessel disease as a cause of brain injury and subsequent and subsequent disability, which may have implications for prevention and treatment."
研究人员得出结论，这些和其它的一些发现“支持了小血管疾病作为脑损伤和继发症以及继发功能障碍的重要原因，这有可能为今后的预防和治疗带来提示。
老年人的视网膜血管状态可以反应脑内小血管的情况
纽约 路透社健康专栏2月12日 — 据研究人员报道，在老年人的颅内磁共振成像和视网膜成像存在某些关联，即较为年轻的受试者存在小血管疾病已经确认。
首席研究员 W. T. Longstreth 医师向路透社健康专栏透露，“视网膜的小血管疾病增加患病风险的可能性的证据已在脑部发现，”另外他补充道“在已经报道的中年人群中二者的关联性要比中年以上人群更为显著。”
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作者:admin@医学,生命科学 2011-02-17 05:11
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