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【文摘发布】左房钙化血栓
Author：Joseph M. Pappachan, M.D. Benjamin C. Bino, M.D.
Resource：N Engl J Med. 2007 Mar 8;356(10):e9.
Impact Factor： 44.016（2005）
Summary：A 21-year-old woman with a history of rheumatic fever at 7 years of age presented with left-sided weakness. A large ischemic infarction involving the territory of the right middle cerebral artery was diagnosed. Cardiac evaluation revealed atrial fibrillation. Echocardiography showed normal aortic, pulmonic, and tricuspid valves, severe mitral stenosis with a valve area of 0.9 cm2, and a large free-floating ball-valve thrombus in the dilated (to 5 cm in diameter) left atrium (Panels A and B, arrows), which partially obstructed the mitral valve intermittently (Panels C and D, arrows, and video). After initial stabilization, the patient was treated with digoxin, warfarin, and penicillin G benzathine at a dose of 1.2 million units every 21 days. After 6 months of physical therapy, she underwent an open mitral valvotomy with removal of the ball-valve thrombus and an increase in the mitral-valve area to 2.8 cm2. Rheumatic heart disease remains a major health issue in India, with one recent study estimating the prevalence as 6.8 cases per 10,000 schoolchildren. Our patient is doing well after surgery, with minimal residual left hemiparesis and facial weakness.
PMID: 17347456 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领 放弃认领 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领 Title：Calcified Left Atrial Thrombus
题目：左房钙化血栓
Author：Joseph M. Pappachan, M.D. Benjamin C. Bino, M.D.
作者：Joseph M. Pappachan ，Benjamin C. Bino
Resource：N Engl J Med. 2007 Mar 8;356(10):e9.
来源：新英格兰医学杂志2007，356（10）：e9
Impact Factor： 44.016（2005）
影响因子：44.016（2005）
提要：一位曾在7岁时有风湿热病史的21岁女性发作左侧肢体无力，诊断为右大脑中动脉支配区域出现缺血梗死。心血管检查发现房颤，心超示：正常主动脉、肺动脉、三尖瓣，严重的二狭，瓣口面积仅为0.9cm2。在扩大的左房里存在巨大的漂浮血栓，血栓间歇性阻塞二尖瓣的开闭。患者初步稳定后，给予地高辛、发法令和每21天一次长效青霉素治疗。经过六个月治疗后，患者接受了一次二尖瓣切开术，取出血栓并且瓣口面积增加到2.8。在印度，风湿性心脏病仍然是威胁人类健康的一个主要问题。最近的一项调查显示，每10000名学生中，患病率为6.8。该病人手术恢复很好，仅残留轻度的左侧偏瘫和面神经无力。
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作者:admin@医学,生命科学 2011-04-26 05:11
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