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【文摘发布】[Nephrology] 肾移植患者感染登革热的
题目：Dengue has a benign presentation in renal transplant patients: A case series.
作者：Renaud CJ, Manjit K, Pary S.
摘要：Aim: Dengue fever and its complications are a poorly described entity in the renal transplant population. Previous reports in renal transplant patients suggest a high mortality rate. Methods: We undertook a retrospective study of six cases of dengue fever in renal transplant patients during a dengue outbreak in Singapore in 2005 which involved a total of 1400 cases in the city state. Results: Mean thrombocytopenia was 130 000/muL on presentation and 80 000/muL at deffervescence. No dengue haemorrhagic fever, dengue shock syndrome, deaths or abnormal graft function were observed. Mean hospital stay was 8.6 days. Four of six patients also had simultaneous CMV reactivation. Conclusion: In common with the majority of adults, dengue fever follows a benign course in the renal transplant population and dengue haemorrhagic fever is rare. This may be related to the relative immunosuppression reducing the risk for antibody-enhanced complications.
PMID: 17498128 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 来源：Nephrology (Carlton). 2007 Jun;12(3):305-7.
来源：肾脏学(Carlton). 2007 Jun;12(3):305-7.
题目：Dengue has a benign presentation in renal transplant patients: A case series.
题目：登革热在肾移植中的良性表现：病例分析
作者：Renaud CJ, Manjit K, Pary S.
摘要：
Aim: Dengue fever and its complications are a poorly described entity in the renal transplant population. Previous reports in renal transplant patients suggest a high mortality rate.
摘要：
目的：登革热及其并发症在肾移植群体中鲜见报道。以往的报道称该病在肾移植病人中具有高死亡率。
Methods: We undertook a retrospective study of six cases of dengue fever in renal transplant patients during a dengue outbreak in Singapore in 2005 which involved a total of 1400 cases in the city state.
方法：我们对六例患登革热的肾移植患者进行了回顾性分析，所有患者均是于2005年新加坡暴发登革热时患病，此次暴发共有1400人患病。
Results: Mean thrombocytopenia was 130 000/muL on presentation and 80 000/muL at deffervescence. No dengue haemorrhagic fever, dengue shock syndrome, deaths or abnormal graft function were observed. Mean hospital stay was 8.6 days. Four of six patients also had simultaneous CMV reactivation.
结果：发病期和缓解期的血小板分别为130 000/muL和80 000/muL。未见登革热型出血热、登革热休克综合征、死亡或移植物功能异常。平均住院日为8.6天。6例患者中有4例同时出现了CMV的再激活。
Conclusion: In common with the majority of adults, dengue fever follows a benign course in the renal transplant population and dengue haemorrhagic fever is rare. This may be related to the relative immunosuppression reducing the risk for antibody-enhanced complications.
结论：与大多数成人一样，在肾移植患者中登革热呈现为良性病程，并且登革热型出血热很少发生。这可能是由于免疫抑制，从而降低了由抗体引起的并发症的风险。
编译后：约350字
Renaud CJ及其同事对登革热在肾移植患者中的表现进行了病例分析，研究结果发表在2007.6的肾脏学杂志。登革热及其并发症在肾移植群体中鲜见报道。以往的报道称该病在肾移植病人中具有高死亡率。研究人员对六例患登革热的肾移植患者进行了回顾性分析，所有患者均是于2005年新加坡暴发登革热时患病，此次暴发共有1400人患病。发病期和缓解期的血小板分别为130 000/muL和80 000/muL。结果显示，病例中未见登革热型出血热、登革热休克综合征、死亡或移植物功能异常。平均住院日为8.6天。6例患者中有4例同时出现了CMV的再激活。据此，研究人员认为，与大多数成人一样，在肾移植患者中登革热呈现为良性病程，并且登革热型出血热很少发生。这可能是由于免疫抑制，从而降低了由抗体引起的并发症的风险。 [标签:content1][标签:content2]
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作者:admin@医学,生命科学 2011-03-11 17:11
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