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【文摘发布】心房粘液瘤的中枢神经系统表现
Author：Lee VH, Connolly HM, Brown RD Jr.
Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA. vivien_lee@rush.edu
Resource: Arch Neurol. 2007 Aug;64:1115-20.
Abstract：BACKGROUND: Neurologic complications can be the initial manifestation of atrial myxoma. Prompt diagnosis is of paramount significance to prevent recurrent complications. OBJECTIVE: To identify patients with neurologic complications attributed to atrial myxoma. DESIGN, SETTING, AND PATIENTS: With institutional review board approval, we retrospectively reviewed the medical records of 74 consecutive patients with pathologically confirmed cardiac myxoma at the Mayo Clinic from January 1, 1993, through December 31, 2004. MAIN OUTCOME MEASURES: Discharge and follow-up modified Rankin score. RESULTS: Nine of the 74 patients with cardiac myxoma (12%) presented with neurologic manifestations in the setting of atrial myxoma. Mean age was 48.5 years (range, 17-70 years). There were 6 females and 3 males. Among patients with myxoma and neurologic symptoms, ischemic cerebral infarct was the most common neurologic manifestation (8 patients [89%]). No patients had concomitant cardiac symptoms. The size of the atrial myxoma was variable, with a mean diameter of 2.7 (range, 0.4-6.5) cm. Most of the atrial myxomas causing neurologic symptoms demonstrated a mobile component on transesophageal echocardiography (8 patients [89%]). Two patients (22%) had pathologic evidence of systemic myxomatous emboli. One patient with intracerebral hemorrhage had pathologically confirmed intracranial metastatic myxoma and myxoma-induced aneurysmal dilatation. CONCLUSIONS: Neurologic complications are associated with cardiac myxoma in some patients with myxoma and, when they occur, frequently present with cerebral infarction. The mobility, not the size, of the myxoma appears to be related to embolic potential. Potential delayed neurologic complications relevant to patients with tumor embolization include myxoma-induced cerebral aneurysm and myxomatous metastasis, which can mimic the clinical picture of central nervous system vasculitis or infective endocarditis.
PMID: 17698701 简单看看,发现其实很难译!请指正!
Title：Central nervous system manifestations of cardiac myxoma.
题目:心房黏液瘤的中枢神经系统表现心表现房粘液瘤的中枢神经系统表现
Author：Lee VH, Connolly HM, Brown RD Jr.
作者: Lee VH, Connolly HM, Brown RD Jr.
Department of Neurology, Mayo Clinic College of Medicine,
梅亚医学院神经科,罗切斯特,明尼苏达州,美国
Rochester, Minnesota, USA.
邮箱:vivien_lee@rush.edu
Resource: Arch Neurol. 2007 Aug;64 :1115-20.
资料来源: Arch Neurol. 2007 Aug;64 :1115-20.
Abstract：BACKGROUND:
摘要:背景:
Neurologic complications can be the initial manifestation of atrial myxoma.
神经系统的并发症可能是心房黏液瘤的初期表现.
Prompt diagnosis is of paramount significance to prevent recurrent complications.
快速诊断的重要意义在于为了预防并发症的再发生.
OBJECTIVE:
目标:
To identify patients with neurologic complications attributed to atrial myxoma.
鉴别心房黏液瘤神经系统并发症的病人
DESIGN, SETTING, AND PATIENTS:
设计,方案和入选病人:
With institutional review board app roval, we retrospectively reviewed the medical records of 74 consecutive patients with pathologically confirmed cardiac myxoma at the Mayo Clinic from January 1, 1993, through December 31, 2004.
我们回顾了梅亚医学院从1993年元月1日到2004年12月31日病理证实为心房黏液瘤的74例病人的住院病历.
MAIN OUTCOME MEASURES:
主要结果指标:
Discharge and follow-up modified Rankin score.
出院和追踪随访
RESULTS:
结果
Nine of the 74 patients with cardiac myxoma (12%) presented with neurologic manifestations in the setting of atrial myxoma.
74例中有9人(12%)的心房黏液瘤病人表现出神经系统并发症.
Mean age was 48.5 years (range, 17-70 years).
平均年龄48.4岁(17-70岁)。
There were 6 females and 3 males.
包括6例女性和3例男性.
Among patients with myxoma and neurologic symptoms,
在黏液瘤并发神经系统症状的患者中,
ischemic cerebral infarct was the most common neurologic manifestation (8 patients [89%]).
脑梗死是最常见的神经并发征(8例[89%]).
No patients had concomitant cardiac symptoms.
没有患者伴发心脏症状.
The size of the atrial myxoma was variable, with a mean diameter of 2.7 (range, 0.4-6.5) cm.
心房黏液瘤的大小是可变的,平均直径2.7(范围,0.4-6.5) cm
Most of the atrial myxomas causing neurologic symptoms demonstrated a mobile component on transesophageal echocardiography (8 patients [89%]).
经食道超声心动图显示并发神经系统症状的大部分心房黏液瘤的成分是可变的(8例[89%]).
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作者:admin@医学,生命科学 2011-08-13 05:11
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