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【medical-news】禽流感疫苗正丧失效力

http://www.medicalnewstoday.com/healthnews.php?newsid=57122
Bird Flu Vaccines Lose Their Strength



The initial doses of bird flu vaccines that were stockpiled by US authorities are less effective now - they lose their strength over time. As the vaccines have a shorter 'shelf-life' than was first expected, it is possible that the US stockpile would now cover one million fewer people than previously thought.

In other words - as the vaccines have a shorter shelf-life than we had previously thought, many of the first ones that were bought may now not be so good.
(Shelf life = How long a drug can be kept/stored before it has to be thrown away. A bit like 'expiry date' on foods. If a drug has a two-year shelf life and was made on 1 January, 2007, it must be discarded by the end of 2008.)

Authorities may have to re-think their contingency plans. It was first thought that by having large stocks of H5N1 vaccines, a nation would be better prepared against a possible pandemic by vaccinating health workers, key personnel and other high-risk groups.

Even so, authorities stressed that the loss of strength is gradual, not total. It does not mean that the strength of the oldest vaccines in stock have gone down from 100 to zero.

Novartis Wins Contract To Top Up USA H5N1 Vaccine Stockpile

Novartis has been awarded a $40.95 million contract to top up the USA's bird flu vaccine stockpile. US authorities aim to have enough vaccines to cover 20 million people. Last year Novartis was awarded a $62.5 million contract.

The pre-pandemic egg-based vaccine will be manufactured by Novartis in 2007 in Liverpool, UK.

Written by: Christian Nordqvist
Editor: Medical News Today 本人已经认领此文. 如在48小时内未能提交译文, 其他战友可自由认领 The initial doses of bird flu vaccines that were stockpiled by US authorities are less effective now - they lose their strength over time. As the vaccines have a shorter 'shelf-life' than was first expected, it is possible that the US stockpile would now cover one million fewer people than previously thought.
由美国当局所初储存的禽流感疫苗首次剂量的效力正减弱,,他们失去了实力.
由于疫苗的保存期比当初预期要短,这可能导致现在美国库存只能满足一百万人,远远少于以前预想的.

In other words - as the vaccines have a shorter shelf-life than we had previously thought, many of the first ones that were bought may now not be so good.
换句话说--由于疫苗保存期比我们原先预料的短,,许多人买的这首次剂量疫苗效力可能不会那么好.

(Shelf life = How long a drug can be kept/stored before it has to be thrown away. A bit like 'expiry date' on foods. If a drug has a two-year shelf life and was made on 1 January, 2007, it must be discarded by the end of 2008.)
Shelf life是指药品在失效前的保存时间.有点象食品的到期时间

Authorities may have to re-think their contingency plans. It was first thought that by having large stocks of H5N1 vaccines, a nation would be better prepared against a possible pandemic by vaccinating health workers, key personnel and other high-risk groups.
当局必须重新考虑应变计划.最初的想法是进行大量的H5N1疫苗储备,一个民族能通过对健康人群,关键人员及其他高危人群进行疫苗接种对付可能出现的大流行疾病.

Even so, authorities stressed that the loss of strength is gradual, not total. It does not mean that the strength of the oldest vaccines in stock have gone down from 100 to zero.
即使如此,当局强调药效是逐渐丧失,不能完全一下子丧失.这并不意味着储存时间最长疫苗效力从100下降至零.

Novartis Wins Contract To Top Up USA H5N1 Vaccine Stockpile
诺华公司赢得了补足美国的H5N1疫苗库存的合同

Novartis has been awarded a $40.95 million contract to top up the USA's bird flu vaccine stockpile.US authorities aim to have enough vaccines to cover 20 million people. Last year Novartis was awarded a $62.5 million contract
诺华已签署价值4095.0万补足USA的禽流感疫苗库存的合同单.美国当局现有足够的疫苗可以应对2000万人患者.去年诺华又拿到62500000美元的合同定单

The pre-pandemic egg-based vaccine will be manufactured by Novartis in 2007 in Liverpool, UK.
前流行的以蛋为基础的疫苗将于2007年在诺华利物浦硕士人工制造来 As the vaccines have a shorter 'shelf-life' than was first expected, it is possible that the US stockpile would now cover one million fewer people than previously thought. Authorities may have to re-think their contingency plans. It was first thought that by having large stocks of H5N1 vaccines, a nation would be better prepared against a possible pandemic by vaccinating health workers, key personnel and other high-risk groups.

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作者:admin@医学,生命科学    2011-06-17 05:14
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