主页 > 医学讨论 >
【medical-news】新的WHO网络工具增进了临床试验的
新的WHO网络工具增进了临床试验的透明度
4 MAY 2007 | GENEVA -- WHO today launched a new web site that will enable researchers, health practitioners, consumers, journal editors and reporters to search more easily and quickly for information on clinical trials. The site works as an entry point or portal into multiple, high quality clinical trial registers with a global search function.
2007-5-4日内瓦——WHO今天新开的网站将为研究者、医疗创业者、消费者、杂志编辑和记者提供更加方便快捷的临床试验信息检索。这个网站相当于一个进入全球大量高质量临床试验记录的入口。
For a doctor or a patient, identifying all clinical trials relevant to a decision to receive a specific treatment option is a difficult task, made easier if the results have been reported in the published literature. However, a significant proportion of research is never published and, even if it is published, it is possible that only part of the story is told in the publication. Relying on information provided only by published trial research is therefore unreliable and leads to inadequately informed treatment decisions.
对医生或患者来说，要弄清所有相关的临床试验再来决定选择某一治疗方案是不太可能的，但是如果这些结果已经在文献中报道过，那就很容易了。然而一大部分研究是从未发表过的，就算发表，也就是研究的一小部分。所以依赖发表的试验研究提供的信息是不可靠的，必将导致治疗决策的信息不全。
The only way to ensure the availability of complete and accurate information about clinical trials is for all trials to be registered before any participants are recruited. WHO believes that the registration of clinical trials is a scientific, ethical and moral responsibility.
保证临床试验信息的全面和准确的唯一办法就是在所有的试验都必须在招募参与者之前进行登记。WHO相信临床试验登记是具有科学、伦理和道德责任的。
“The Clinical Trial Search Portal is a collaborative, international initiative led by WHO that facilitates the identification of all clinical trials, regardless of whether or not they have been published. For health care researchers, funders, policy-makers and consumers the portal represents an enormous step towards greater access, transparency and accountability of health research globally,” said Tim Evans, Assistant Director General, Information Evidence and Research, WHO. The portal is accessible at http://www.who.int/trialsearch.
“‘临床试验研究入口’是一项WHO领到的全球合作的初试，将推进所有临床试验的鉴析，而不管其是否发表。对于医疗保健研究者、基金持有者、决策者和消费者来说，该入口向着具有更大访问量、透明度和责任性的世界医学研究卖出了一大步。”WHO信息证据和研究助理总干事Tim Evans说。
Navigation, accuracy problems
导航，准确性问题
Clinical trial registers have now become widely accepted as an essential part of an overall strategy for improving health outcomes. The challenge now facing those wanting to identify clinical trials research is knowing how to navigate their way through the ever increasing number of registers that now exist, and knowing which registers provide information that is accurate and reliable.
临床研究登记被公认为是提高治疗结果全面计划的关键部分。要想弄清临床试验研究面临着许多挑战，包括如何在目前不断增加的登记数中导航，哪个登记提供的信息是正确可靠的。
The quality of information accessible through the WHO portal is assured as registers providing data to the search portal are all collaborators in the WHO Network of Collaborating Clinical Trial registers, also announced today. The network will provide a forum for registers to exchange information and work together to establish best practice for clinical trial registration. Registers in the network that contribute data to the search portal have agreed to prospectively register trials, are able to collect all 20 items in the WHO Trial Registration Data Set and have mechanisms in place to ensure the optimal quality of the data provided. They are also required to publicly disclose their ownership, governance structure and for-profit status. Details of registers meeting the required standards are available on the web site.
通过WHO入口获取的信息的质量是有保证的，因为提供给研究入口的资料登记都为WHO临床研究合作登记中的合作者。网络会为登记者提供一个论坛来交流信息，为建立临床试验登记的最好操作方式共同合作。在为研究入口提供资料的网络上，同意预先登记试验的登记者将会收集到WHO试验登记资料中的20个项目，内有确保提供资料最佳质量的机制。还要求他们公布他们的拥有关系，管理结构和利润状态。只有符合要求标准的登记者的详情才能被查询到。
阅读本文的人还阅读：
作者:admin@医学,生命科学 2011-02-16 05:11
医学,生命科学网