主页 > 医学讨论 >

【medical-news】包皮环切术降低宫颈癌危险因素的

Male circumcision lowers cervical cancer risk: study

By Maggie Fox, Health and Science Editor

WASHINGTON (Reuters) - Three studies published on Wednesday add to evidence that circumcision can protect men from the deadly AIDS virus and the sexually transmitted virus that causes cervical cancer.

The reports in the Journal of Infectious Diseases are likely to add to the debate over whether men -- and newborn boys -- should be circumcised to protect their health and perhaps the health of their future sexual partners.

Dr. Bertran Auvert of the University of Versailles in France and colleagues in South Africa tested more than 1,200 men visiting a clinic in South Africa,

They found under 15 percent of the circumcised men and 22 percent of the uncircumcised men were infected with the human papilloma virus, or HPV, which is the main cause of cervical cancer and genital warts.

"This finding explains why women with circumcised partners are at a lower risk of cervical cancer than other women," they wrote in their report.

A second paper looking at U.S. men had less clear-cut results, but Carrie Nielson of Oregon Health & Science University and colleagues said they found some indication that circumcision might protect men.

The circumcised men were about half as likely to have HPV as uncircumcised men, after adjustment for other differences between the two groups.

PREVENTING AIDS

In the third report, Lee Warner of the U.S. Centers for Disease Control and Prevention and colleagues tested African-American men in Baltimore and found 10 percent of those at high risk of infection with HIV who were circumcised had the virus, compared to 22 percent of those who were not.

"Circumcision was associated with substantially reduced HIV risk in patients with known HIV exposure, suggesting that results of other studies demonstrating reduced HIV risk for circumcision among heterosexual men likely can be generalized to the U.S. context," they wrote.

Studies supporting circumcision to reduce HIV transmission had all been done in Africa and U.S. studies were less clear.

Dr. Ronald Gray of Johns Hopkins University in Baltimore and colleagues said they found the reports encouraging.

"In the United States, circumcision is less common among African American and Hispanic men, who are also the subgroups most at risk of HIV," they wrote in a commentary.

"Thus, circumcision may afford an additional means of protection from HIV in these at-risk minorities."

But they noted that the American Academy of Pediatrics does not recommend routine circumcision for newborns.

"As a consequence of this AAP decision, Medicaid does not cover circumcision costs, and this is particularly disadvantageous for poorer African American and Hispanic boys who, as adults, may face high HIV exposure risk," Gray and colleagues wrote.

"It is also noteworthy that circumcision rates have been declining in the U.S., possibly because of lack of Medicaid coverage."

Medicaid is the state-federal health insurance program for the poor and disabled.

Thirty-three million people globally are infected with AIDS, which has no cure and no vaccine. HPV is the most common sexually transmitted infection in the world, with 20 million people in the United States infected. It causes cervical cancer, which kills 300,000 women globally every year. 本人已认领该文编译,48小时后若未提交译文,请其他战友自由认领。 Male circumcision lowers cervical cancer risk: study
男性包皮环切术降低宫颈癌危险度研究
By Maggie Fox, Health and Science Editor

WASHINGTON (Reuters) - Three studies published on Wednesday add to evidence that circumcision can protect men from the deadly AIDS virus and the sexually transmitted virus that causes cervical cancer.
周三刊出的三项研究增加了包皮环切术能够保护男性免受致命的艾滋病病毒以及导致宫颈癌的性传播病毒危害的证据。
The reports in the Journal of Infectious Diseases are likely to add to the debate over whether men -- and newborn boys -- should be circumcised to protect their health and perhaps the health of their future sexual partners.
传染病杂志上的这篇文章似乎重新挑起了争论,关于男性以及新生男婴是否应该为了他们以及将来性伴侣的健康而进行包皮环切术。
Dr. Bertran Auvert of the University of Versailles in France and colleagues in South Africa tested more than 1,200 men visiting a clinic in South Africa,
法国凡尔赛大学的Bertran Auvert医生和他的南非同事们对1200多位就诊于南非某诊所的男性患者进行了研究。
They found under 15 percent of the circumcised men and 22 percent of the uncircumcised men were infected with the human papilloma virus, or HPV, which is the main cause of cervical cancer and genital warts.
他们发现15%的术后男性和22%的未手术男性感染了人乳头瘤病毒即HPV,而它是宫颈癌和尖锐湿疣的主要病因。

阅读本文的人还阅读:

【技术产业】默克宫颈癌

【J Clin Oncol】乳腺癌后淋

作者:admin@医学,生命科学    2011-02-13 17:11
医学,生命科学网