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【medical-news】超声心动图提示左室壁运动异常可
13 July 2007
MedWire News: Adults with echocardiographic left ventricular wall motion (WM) abnormalities but no overt cardiovascular disease have a substantially increased risk for cardiovascular morbidity and mortality, regardless of the presence of established risk factors, say scientists.
Left ventricular WM abnormalities have a recognized prognostic significance among patients with coronary or other heart diseases, but it is not clear whether such abnormalities predict adverse events in people without overt cardiovascular disease.
To investigate further, Richard Devereux, from Weill Medical College of Cornell University in New York, USA and colleagues studied 2864 participants from the second Strong Heart Study, who did not have clinically evident cardiovascular disease and had an average age of 60 years.
All of the participants underwent complete echocardiographic WM assessment, which indicated that 5% of them had focal hypokinesia, while 1.5% were found to have WM abnormalities, the team writes in the journal Circulation.
Over an average of 8.2 years of follow-up, 554 participants experienced fatal and nonfatal cardiovascular events, including myocardial infarction, stroke, coronary artery disease, and heart failure. A further 182 patients experienced cardiovascular death.
After taking into account age, gender, waist/hip ratio, systolic blood pressure, and the presence of diabetes mellitus, the team discovered that segmental WM abnormalities were linked to an increased risk for cardiovascular events, at an adjusted hazard ratio of 2.5, and cardiovascular death, at a hazard ratio of 2.6. For global WM abnormalities, the researchers calculated that the adjusted hazard ratio for cardiovascular events was 2.4, while that for cardiovascular death was 3.4.
“The present population-based study of adults without clinically evident cardiovascular disease demonstrates a strong relationship between the presence of WM abnormalities and cardiovascular events and death,” the team writes.
“These findings suggest that echocardiographic assessment of regional left ventricular dysfunction can identify adults without know cardiovascular disease who are at increased risk of future cardiovascular events.”
Circulation 2007; 116: 143–150Circulation 2007; 116: 143–150
http://www.incirculation.net/NewsItem/LV-wall-motion-abnormalities-alone-predict-cardiov.aspx 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 LV wall motion abnormalities alone predict cardiovascular morbidity, mortality
左心室室壁运动异常可单独预测心血管病发病率和死亡率
13 July 2007
2007年7月13日
MedWire News: Adults with echocardiographic left ventricular wall motion (WM) abnormalities but no overt cardiovascular disease have a substantially increased risk for cardiovascular morbidity and mortality, regardless of the presence of established risk factors, say scientists.
MedWire新闻：科学家称，超声心动图显示左心室室壁运动（WM）异常而无心血管疾病的成人，不管其是否存在其他已知的危险因素，其心血管疾病的发病率和死亡率都显著增加。
Left ventricular WM abnormalities have a recognized prognostic significance among patients with coronary or other heart diseases, but it is not clear whether such abnormalities predict adverse events in people without overt cardiovascular disease.
左心室WM异常在冠心病或其他心脏疾病患者中具有公认的预测价值，但是，它能否预测无心血管疾患的成人发生不良事件的风险目前还不清楚。
To investigate further, Richard Devereux, from Weill Medical College of Cornell University in New York, USA and colleagues studied 2864 participants from the second Strong Heart Study, who did not have clinically evident cardiovascular disease and had an average age of 60 years.
纽约康奈尔大学Weill医学院Richard Devereux和同事对the second Strong Heart Study中的2864名参与者进行了研究，这些参与者均无临床心血管疾病的证据，平均年龄60岁。
All of the participants underwent complete echocardiographic WM assessment, which indicated that 5% of them had focal hypokinesia, while 1.5% were found to have WM abnormalities, the team writes in the journal Circulation.
所有参与者都接受了完整的超声心动图WM评估，其中5%显示有局部运动减弱， 1.5%有WM异常，作者在《Circulation》杂志上称。
Over an average of 8.2 years of follow-up, 554 participants experienced fatal and nonfatal cardiovascular events, including myocardial infarction, stroke, coronary artery disease, and heart failure. A further 182 patients experienced cardiovascular death.
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作者:admin@医学,生命科学 2011-02-17 18:04
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