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【文摘发布】AJOG(2007年6月）——产前和产时死胎
产前产时死胎的危险因素
Darios Getahun, MD, MPHa1, Cande V. Ananth, PhD, MPHa1, Wendy L. Kinzler, MDb
To examine disparities in risk factors for stillbirths and its occurrence in the antepartum versus intrapartum periods.
本研究是为了考察产前和产时死胎发生的危险因素的差异。
A population-based, cross-sectional study using data on women that delivered singleton births between 20 and 43 weeks in Missouri (1989-1997) was conducted (n = 626,883).
本研究基于人口学的横断面研究。所选择的对象是1989-1997年密苏里州生育一胎的妇女，年龄由20岁-43岁。
Hazard ratios and 95% confidence intervals were derived from regression models and population attributable fractions were estimated to examine the impact of risk factors on stillbirth.
由回归模型得到危险比和95%可信区间，评估人口可归因的部分以评价危险因素对死产的影响作用的大小。
Among African Americans, risks of antepartum and intrapartum stillbirth were 5.6 and 1.1 per 1,000 singleton births, respectively; risks among whites were 3.4 and 0.5 per 1,000 births, respectively.
在非裔美国人中，产前产时死胎发生的危险率分别是5.6/1000和1.1/1000；白人是3.4/1000和0.5/1000.
Maternal age ≥35 years, lack of prenatal care, prepregnancy body mass index (BMI) ≥ 30 kg/m2, and prior preterm or small-for-gestational age birth were significantly associated with increased risk for antepartum stillbirth among whites, but not African Americans.
在白人中，母亲年龄≥35 years、缺少产前保健、怀孕前体重指数(BMI) ≥ 30 kg/m2以及早产及小于胎龄是发生产前死胎有意认的危险因素，而非裔美国人则无意义。
BMI ≤18.5 kg/m2 was associated with antepartum and intrapartum stillbirth among African Americans, but not whites.
对于非裔美国人而非白人，BMI ≤18.5 kg/m2是发生产前及产时死胎的危险因素。
The presence of any congenital anomaly, abruption, and cord complications were associated with antepartum stillbirth in both races.
任何先天性畸形、分裂、合并症是白人及非裔美国人发生产前死胎的危险因素。
Premature rupture of membranes was associated with intrapartum stillbirth among whites and African Americans, but intrapartum fever was associated with intrapartum stillbirth among African Americans.
对于白人及非裔美国人，胎膜早破与分娩期内死产有意义， 而产时发热仅对非裔美国人发生非裔美国人有意义。
These risk factors were implicated in 54.9% and 19.7% of antepartum and intrapartum stillbirths, respectively, among African American women, and in a respective 46.6% and 11.9% among white women.
对于非裔美国人，这些危险因素在产前及产时死胎中所占比例分别是54.9%和19.7%，而白人是46.6%和11.9%。
Considerable heterogeneity in risk factors between antepartum and intrapartum stillbirths is evident. Knowledge on timing of stillbirth specific risk factors may help clinicians in decreasing antepartum and intrapartum stillbirth risks through monitoring and timely intervention.
非常明显，产前和产时死胎的危险因素存在相当大的不一致性。掌握死产特异的危险因素发生的时机有助于临床医生通过监测及适时介入，减少分娩前及分娩时死胎发生的危险.
optimismzhuzhu wrote:
Risk factors for antepartum and intrapartum stillbirth: a population-based study 谢谢你的指导，文中的一些专业术语我没有翻译出来，你改正后，我学会了。 编译如下：
产前产时死胎的危险因素
本研究是为了考察产前和产时死胎发生的危险因素的差异。
本研究基于人口学的横断面研究。所选择的对象是1989-1997年密苏里州生育一胎的妇女，孕周为20岁-43周。
由回归模型得到危险比和95%可信区间，评估人口可归因的部分以评价危险因素对死产的影响作用的大小。
在非裔美国人中，产前产时死胎发生的危险率分别是5.6/1000和1.1/1000；白人是3.4/1000和0.5/1000.
在白人中，母亲年龄≥35 years、缺少产前保健、怀孕前体重指数(BMI) ≥ 30 kg/m2以及早产及小于胎龄是发生产前死胎有意认的危险因素，而非裔美国人则无意义。
对于非裔美国人而非白人，BMI ≤18.5 kg/m2是发生产前及产时死胎的危险因素。
任何先天性畸形、胎盘早剥、脐带合并症是白人及非裔美国人发生产前死胎的危险因素。
对于白人及非裔美国人，胎膜早破与分娩期内死产有意义， 而在非裔美国人中产时发热与死产有关。阅读本文的人还阅读：
作者:admin@医学,生命科学 2011-03-06 05:12
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