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【medical-news】小腿活动强度：反映COPD病人全天活
NEW YORK (Reuters Health) Aug 13 - Simple monitoring of leg movement in patients with chronic obstructive pulmonary disease gives a good indication of total daily activity, investigators report. While activity is lower than in control patients, it improves with pulmonary rehabilitation.
"Patients with chronic obstructive pulmonary disease (COPD) walk less than healthy older people and their self-reported activity predicts exacerbation risk," Dr. P. P. Walker, of the University of Liverpool, UK, and colleagues write in the August issue of Thorax. "The relationship between lower limb activity and total daily activity is not known, nor are there any data that relate objectively assessed daily activity to laboratory assessments made before and after rehabilitation."
The researchers measured lower limb activity by leg actigraphy over 3 days in 45 patients with moderate to severe COPD and 18 control subjects of similar age.
The mean leg activity level and the mean whole body activity level were closely related in COPD patients, but leg activity in COPD patients was consistently reduced compared to control subjects.
The authors report that the mean activity of the legs, mean intensity of leg activity, and the percentage of time patients spent mobile at home were all related to FEV1. However, intensity of activity was not related to the amount of time spent mobile.
Thirty-three COPD patients were enrolled in an 8-week pulmonary rehabilitation program. Those who completed rehabilitation had significant improvements in mean activity and spent more time mobile. These changes were not related to improvement in walking distance or muscle strength. However, they were positively correlated with baseline FEV1.
"Our data provide further support for the usefulness of monitoring daily activity at home in patients with COPD and confirm that simple monitoring of leg movement gives useful insights into daily activity," Dr. Walker's team concludes. "The intensity and amount of leg activity a patient undertakes at home gives rather different results from those predicted by more conventional measurements such as walking distance, muscle strength and health status questionnaires."
Thorax 2008;63:683-689.
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作者:admin@医学,生命科学 2010-11-23 05:11
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