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【drug-news】CSL公司发现Gardasil疫苗加强剂

http://www.news.com.au/business/story/0,23636,20846807-31037,00.html
CSL to fund Gardasil booster
November 30, 2006 10:17am
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BIOTECHNOLOGY company CSL has promised to help fund a booster to the cervical cancer vaccine Gardasil if its effectiveness diminishes in time.

Prime Minister John Howard yesterday announced schoolgirls will begin being immunised with Gardasil from next April after the government struck a deal with CSL (csl.ASX:Quote,News).

The company has agreed to a 25 per cent cut in its original $600 million asking price for the four-year program, which will now cost $436 million.

Earlier this month, the government's Pharmaceutical Benefits Advisory Committee (PBAC) controversially rejected CSL's proposal to immunise all 12- to 26-year-old women saying it was not cost effective.

But after re-evaluating the proposal, under pressure from the government, the PBAC gave its approval to the revised program.

PBAC Chairman Professor Emeritus Lloyd Sansom said although the process was rushed, it was identical to the process used for approving other pharmaceuticals.

"The only difference in this one has been that the resubmission was considered earlier than is normal because the government had indicated to PBAC that if the PBAC could come to a positive recommendation then they would wish to implement this in the 2007 school year," Professor Sansom said on ABC radio today.

"The PBAC was adamant that there was no way in which processes would be allowed to be changed because of this vaccine, and I'm delighted (Health Minister Tony Abbott) was a strong supporter of that."

Professor Sansom said CSL had agreed to be involved in a booster vaccine, if it was needed.

"We don't know what will happen in 10 years or 20 years time," he said.

"That's the uncertainty about the active bacteria in this drug, and therefore we wanted some undertaking from the company that they would pick up some shared responsibility on this regard."

This exercise, he said, had demonstrated the need for the PBAC to provide more timely access to information.

"A lot of the comments made on the side were uninformed because simply the PBAC was not open to provide timely information with respect to why it made its original decision."

Prof Sansom said he already had had discussions with Medicines Australia to examine the matter.

Gardasil guards against the human papilloma virus (HPV), which is spread by sexual intercourse and causes about 70 per cent of cervical cancer cases.

At 1006 AEDT CSL shares were up 46 cents to $59.46. 我认领这个,倘若48小时没做完,请各位高手帮忙! 前言:Booster(免疫增强剂)---免疫增强剂是指单独或同时与抗原使用时能增强机体免疫应答的物质。免疫增强剂的研究涉及免疫学和药学的内容,是最近几年应用医学最活跃的研究领域之一。免疫增强剂的种类繁多,不下十几类上百种,包括矿物质类,如硒、锌等;中草药类,如黄芪、白芍、芦荟、当归等;免疫佐剂类,如蜂胶、弗氏佐剂等;微生物制剂类,如卡介苗、霍乱毒素B亚单位等;维生素类,如维生素A、维生素E等;氨基酸类,如精氨酸、亮氨酸等;激素或激素样物质类,如生长激素、胸腺肽等;核酸制剂类,如多(聚)核苷酸、免疫核糖核酸等;抗寄生虫药物类,如左旋咪唑、甲硝唑等;其它免疫增强剂,如干扰素、蜂花粉、热休克蛋白等。

CSL to fund Gardasil booster
CSL支持 Gardasil增强剂的使用
BIOTECHNOLOGY company CSL has promised to help fund a booster to the cervical cancer vaccine Gardasil if its effectiveness diminishes in time.
生物科技公司CSL承诺如果宫颈癌疫苗Gardasil增强剂确实安全有效,他们将全力推广这种药物。
Prime Minister John Howard yesterday announced schoolgirls will begin being immunised with Gardasil from next April after the government struck a deal with CSL (csl.ASX:Quote,News).
总理John Howard于昨日宣布:按照政府与CSL公司达成的协议,在校女学生将从明年4月开始使用Gardasil疫苗。
The company has agreed to a 25 per cent cut in its original $600 million asking price for the four-year program, which will now cost $436 million.
CSL同意给予价格上25%的优惠,从原来的4年600w降到现在的435w。
Earlier this month, the government's Pharmaceutical Benefits Advisory Committee (PBAC) controversially rejected CSL's proposal to immunise all 12- to 26-year-old women saying it was not cost effective.
月初,政府药物咨询委员会(PBAC)拒绝了CSL提出的对所有12-26岁的女孩进行免疫的提议,委员会认为这样做性价比不高。
But after re-evaluating the proposal, under pressure from the government, the PBAC gave its approval to the revised program.

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作者:admin@医学,生命科学    2011-05-02 05:11
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