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【文摘发布】6-8头颈肿瘤患者放疗后出现甲状腺
Hypothyroidism after radiotherapy for patients with head and neck cancer
American Journal of Otolaryngology–Head and Neck Medicine and Surgery 28 (2007) 46– 49
Hiroyuki Ozawa, MDa,b,4, Hideyuki Saitoua,b, Kunio Mizutari Yasunori Takatad, Kaoru Ogawaa
We report on 2 cases of hypothyroidism presenting clinical symptoms that occurred after radiotherapy for cancer of the head and neck and on the results of estimating thyroid function in patients with head and neck cancer who received radiotherapy. The first patient underwent total laryngectomy for laryngeal cancer without sacrificing the thyroid gland and partial gastrectomy for gastric cancer. Radiotherapy of the neck was carried out postoperatively. Two years later, the patient
developed chest pain; pericardial effusion was detected, leading to a diagnosis of myxedema caused by hypothyroidism. The second patient received radiotherapy alone for laryngeal cancer. Two months later, low serum sodium concentration and anemia were detected in this patient. The cause of these changes was subsequently found to be hypothyroidism. Based on our experience with these 2 cases, we measured thyroid function in 35 patients who had undergone neck radiation for head and
neck cancer at our hospital over the past 10 years. Hypothyroidism was observed in 13 of the 35 patients (37%). The prevalence of hypothyroidism was 46% (6/13) for patients treated with both radiation and surgery, as compared with 32% (7/22) for those who received radiation alone. The risk factors responsible for hypothyroidism were not evident from the statistical analysis of these cases. We believe that thyroid function should be evaluated periodically in patients who have undergone
neck radiation because it is often difficult to diagnose hypothyroidism only from clinical symptoms. 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 头颈肿瘤患者放疗后出现甲状腺功能减退
Hypothyroidism after radiotherapy for patients with head and neck cancer
American Journal of Otolaryngology–Head and Neck Medicine and Surgery 28 (2007) 46– 49
Hiroyuki Ozawa, MDa,b,4, Hideyuki Saitoua,b, Kunio Mizutari Yasunori Takatad, Kaoru Ogawaa
We report on 2 cases of hypothyroidism presenting clinical symptoms that occurred after radiotherapy for cancer of the head and neck and on the results of estimating thyroid function in patients with head and neck cancer who received radiotherapy.
我们报道两例头颈肿瘤患者接受放疗后出现甲状腺功能减退临床症状表现的病例，并对接受放疗的头颈肿瘤患者的甲状腺功能进行评估。[标签:content1][标签:content2]
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作者:admin@医学,生命科学 2011-03-09 13:23
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