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【drug-news】世界10大重磅药,品种,厂家,销量和适应
Lipitor
Maker: Pfizer
Sales Rank: 1
Technology: Chiral chemistry
2009 Sales: $12.5 billion
Indications: Hypercholesterolemia and mixed dyslipidemia (Fredrickson types IIa and IIb) to reduce total cholesterol
Plavix
Maker: Bristol-Myers Squibb and Sanofi-Aventis
Sales Rank: 2
Technology: Small molecule
2009 Sales: $9.5 billion
Indications: Heart attack and stroke prevention
Advair
Maker: GlaxoSmithKline
Sales Rank: 3
Technology: Small Molecule
2009 Sales: $7.7 billion
Indications: Asthma and COPD
Enbrel
Maker: Amgen
Sales Rank: 4
Technology: Recombinant product
2009 Sales: $6.2 billion
Indications: Rheumatoid arthritis, psoriatic arthritis, juvenile idiopathic arthritis, ankylosing spondylitis, chronic plaque psoriasis
Diovan
Maker: Novartis
Sales Rank: 5
Technology: Small Molecule
2009 Sales: $6.0 billion
Indications: Hypertension and congestive heart failure
Remicade
Maker: Johnson & Johnson
Sales Rank: 6
Technology: Monoclonal antibody
2009 Sales: $5.9 billion
Indications: Plaque psoriasis, rheumatoid arthritis, psoriatic arthritis, Crohn's disease in adults, pediatric Crohn's disease, ulcerative colitis, and ankylosing spondylitis
Avastin
Maker: Roche/Genentech
Sales Rank: 7
Technology: Monoclonal antibody
2009 Sales: $5.7 billion
Indications: Metastatic Colorectal Cancer, Non-Small Cell Lung Cancer, Metastatic Breast Cancer, Glioblastoma, Metastatic Kidney Cancer
Rituxan
Maker: Roche/Genentech
Sales Rank: 8
Technology: Monoclonal antibody
2009 Sales: $5.6 billion
Indications: Non-Hodgkin's lymphoma, Chronic Lymhocytic leukemia, Rheumatoid arthritis
Humira
Maker: Abbott Pharmaceuticals
Sales Rank: 9
Technology: Monoclonal antibody
2009 Sales: $5.5 billion
Indications: Rheumatoid arthritis, Polyarticular juvenile idiopathic arthritis, Psoriatic arthritis, Ankylosing spondylitis (AS) in adults, Crohn's disease, Plaque psoriasis
Seroquel
Maker: AstraZeneca
Sales Rank: 10
Technology: Small molecule
2009 Sales: $5.1 billion
Indications: Major depressive disorder, Acute depressive episodes in bipolar disorder, Acute manic or mixed episodes in bipolar disorder alone or with lithium or divalproex; Long-term treatment of bipolar disorder with lithium or divalproex, and Schizophrenia
From Fiercebiotech top blockbuster Rx 很NICE，
有出处的话就更好了。 再加上十大药物的背景知识就好了。 thanks 其中5个抗体药，很NICE 重磅炸***！ 抗体药物的发展越来越快
国内这方面的研究却很欠缺，目前药物的研发经费主要集中在化学药物和天然药物的研究方面，如抗体类这种有着光明前景的生物药却被官员们视而不见。 Lipitor
Maker: Pfizer
Sales Rank: 1
Technology: Chiral chemistry
2009 Sales: $12.5 billion
Indications: Hypercholesterolemia and mixed dyslipidemia (Fredrickson types IIa and IIb) to reduce total cholesterol
立普妥
生产商：辉瑞
销售排名：1
技术：手性药物
2009年销售额：125亿美元
适应症：降血脂，用于高胆固醇血症和混合型高脂血症（Fredrickson IIa 和Iib型）。
Plavix
Maker: Bristol-Myers Squibb and Sanofi-Aventis
Sales Rank: 2
Technology: Small molecule
2009 Sales: $9.5 billion
Indications: Heart attack and stroke prevention
波立维
生产商：百时美施贵宝及赛诺菲安万特
销售排名：2
技术：小分子药物
2009年销售额：95亿美元
适应症：用于防治心肌梗死及脑血栓。
Advair
Maker: GlaxoSmithKline
Sales Rank: 3
Technology: Small Molecule
2009 Sales: $7.7 billion
Indications: Asthma and COPD
Advair
生产商：葛兰素史克
销售排名：3
技术：小分子药物
2009年销售额：77亿美元
适应症：哮喘及慢性阻塞性肺气肿（COPD）
Enbrel
Maker: Amgen
Sales Rank: 4
Technology: Recombinant product
2009 Sales: $6.2 billion
Indications: Rheumatoid arthritis, psoriatic arthritis, juvenile idiopathic arthritis, ankylosing spondylitis, chronic plaque psoriasis
恩利（依那西普）
生产商：安进
销售排名：4
技术：重组生物制剂
2009年销售额：62亿美元
适应症：用于类风湿关节炎、关节性牛皮癣、幼年特发性关节炎、关节强硬性脊椎炎、慢性斑块型牛皮癣。
Diovan
Maker: Novartis
Sales Rank: 5
Technology: Small Molecule
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作者:admin@医学,生命科学 2011-01-26 11:56
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