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【medical-news】【动态版】诊断时分居中的癌症患
ScienceDaily (Aug. 24, 2009) — Among unmarried cancer patients, those who are separated at the time of diagnosis do not live as long as widowed, divorced, and never married patients. That is the conclusion of a new study to be published in the November 1, 2009 issue of Cancer, a peer-reviewed journal of the American Cancer Society. The authors of the study say its results suggest that the stress associated with marital separation may compromise an individual's immune system and lead to a greater susceptibility to cancer.
Research has shown that personal relationships have a significant role in physical health—specifically that good relationships are beneficial and poor relationships are deleterious. Also, many studies of cancer prognosis have found that patients who are married live longer than those who are single. However, little information is available regarding differences in survival among the various types of people who are unmarried.
To look for trends in cancer survival among patients who are separated, divorced, widowed, and never married, researchers led by Gwen Sprehn, Ph.D., of the Indiana University School of Medicine in Indianapolis analyzed data from the Surveillance Epidemiology and End Results (SEER) database, a population-based cancer registry in the United States.
The researchers assessed the 5 and 10 year survival rates of 3.79 million patients diagnosed with cancer between 1973 and 2004. They found that married patients had the highest 5 and 10 year survival rates, at 63.3 percent and 57.5 percent respectively. At the other end of the spectrum, separation carried the poorest survival outcome. Specifically, the 5 and 10 year survival rates for separated patients were 45.4 percent and 36.8 percent respectively. The 5 and 10 year survival rates of widowed patients were the next lowest, at 47.2 percent and 40.9 percent respectively; for divorced patients, the respective survival rates were 52.4 percent and 45.6 percent; and for never married patients, they were 57.3 percent and 51.7 percent.
The authors hypothesized that the stress of separation may compromise the immune system and thus create a greater vulnerability to cancer. While additional research is needed, the researchers say certain interventions might help patients today. For example, psychological interventions to reduce stress may impact the immune system and improve survival.
"Patients who are going through separation at the time of diagnosis may be a particularly vulnerable population for whom intervention could be prioritized," says Sprehn. "Identification of relationship-related stress at time of diagnosis could lead to early interventions which might favorably impact survival. Ideally, future research will study marital status in more detail over time and also address individual differences in genetic profile and biomarkers related to stress, immune, and cancer pathways in order to determine mechanisms which might underlie this possible critical period for cancer pathogenesis 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 相关帖子
【科普】社交回避的心血管危险
http://www.dxy.cn/bbs/post/view?bid=116&id=15382977&sty=1&tpg=1&age=0 Cancer Patients Who Are Separated When Diagnosed Have Worse Survival Rates
诊断时分居中的癌症患者存活率更低
ScienceDaily (Aug. 24, 2009) — Among unmarried cancer patients, those who are separated at the time of diagnosis do not live as long as widowed, divorced, and never married patients. That is the conclusion of a new study to be published in the November 1, 2009 issue of Cancer, a peer-reviewed journal of the American Cancer Society. The authors of the study say its results suggest that the stress associated with marital separation may compromise an individual's immune system and lead to a greater susceptibility to cancer.
在单身的癌症患者中，在诊断的时候分居的病人不如丧偶、离婚、和从来没有结过婚的人存活的时间长。癌症杂志，一个美国癌症协会同行评审的杂志，于2009年11月刊登了一项新的研究中的这一结论。该研究的作者说结果表明与配偶分离的压力可能会损害个体的免疫系统并且会更易引起癌症。
Research has shown that personal relationships have a significant role in physical health—specifically that good relationships are beneficial and poor relationships are deleterious. Also, many studies of cancer prognosis have found that patients who are married live longer than those who are single. However, little information is available regarding differences in survival among the various types of people who are unmarried.
研究者已经证明个人关系在机体健康方面有十分重要的作用，好的关系对健康有利，不好的关系对健康有害。许多关于癌症预后的研究也发现，结了婚的癌症患者比单身的患者存活时间长。然而，在各种各样未婚得到人当中，没有关于其与存活率的结果相关的信息。
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作者:admin@医学,生命科学 2010-10-12 05:11
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