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【medical-news】补充叶酸可预防胎盘早剥
By David Douglas
NEW YORK (Reuters Health) May 01 - Use of folic acid and other vitamin supplements before or during pregnancy appears to reduce the risk of placental abruption, Norwegian researchers report in the April issue of the American Journal of Epidemiology.
Dr. Roy M. Nilsen of the University of Bergen and colleagues studied data on more than 280,000 singleton deliveries recorded in Norway between 1999 and 2004. In total, there were 1070 placental abruptions (0.38%).
Use of folic acid with or without multivitamin supplements before or during pregnancy was reported by 36.4% of those who had abruptions and 44.4% of those who did not.
Compared to no use, any supplement use gave an adjusted odds ratio for abruption of 0.74. For folic acid use alone, the odds ratio was 0.81, and for multivitamin use it was 0.72. The greatest effect was seen in those who had used both types of supplements (adjusted odds ratio, 0.68).
Should such an effect be proven in interventional studies, Dr. Nilsen commented to Reuters Health, "this would extend current recommendations to assure adequate intake of folate before and early in pregnancy to prevent neural tube defects."
Am J Epidemiol 2008;167:867-874.
http://www.medscape.com/viewarticle/573887 本人已认领该文翻译，48小时后若未提交译文，请其他战友自由认领 既然楼上还没给出译文，我重新认领了。 Folate Supplement Cuts Risk of Placental Abruption
By David Douglas
NEW YORK (Reuters Health) May 01 - Use of folic acid and other vitamin supplements before or during pregnancy appears to reduce the risk of placental abruption, Norwegian researchers report in the April issue of the American Journal of Epidemiology.
在妊娠之前或之中补充叶酸和其他维生素可降低胎盘早剥的危险性，据挪威的研究人员在美国流行病学期刊的四月份评论上报道。
Dr. Roy M. Nilsen of the University of Bergen and colleagues studied data on more than 280,000 singleton deliveries recorded in Norway between 1999 and 2004. In total, there were 1070 placental abruptions (0.38%).
Bergen大学的Roy M. Nilsen博士和他的同事们研究了在挪威记录的1999至2004年之间的超过280，000名独生子分娩资料。共有1070名发生胎盘早剥（0.38%）。
Use of folic acid with or without multivitamin supplements before or during pregnancy was reported by 36.4% of those who had abruptions and 44.4% of those who did not.
补充或者不补充多种维生素中，在妊娠前或之中补充叶酸发生早剥的概率为36.4%， 而未补充叶酸早剥的概率为44.4%。
Compared to no use, any supplement use gave an adjusted odds ratio for abruption of 0.74. For folic acid use alone, the odds ratio was 0.81, and for multivitamin use it was 0.72. The greatest effect was seen in those who had used both types of supplements (adjusted odds ratio, 0.68).
相比于未用任何补充者，使用补充物的校正优势比为0.74。而对于单用叶酸者， 优势比为0.81. 对于多种维生素应用者，其为0.72. 最好的效果见于两种补充物均用者（校正优势比，0.68 ）
Should such an effect be proven in interventional studies, Dr. Nilsen commented to Reuters Health, "this would extend current recommendations to assure adequate intake of folate before and early in pregnancy to prevent neural tube defects."
一旦这样的结果在介入研究中被证实，Nilsen博士在路透社健康版评论，“这将会使当前的建议得以流行蔓延，即通过在妊娠之前及妊娠早期确保足够量的叶酸摄入来预防神经管缺陷。
Am J Epidemiol 2008;167:867-874 下面是编译文，望各位高手批评指正。（字数438）
补充叶酸可预防胎盘早剥
纽约路透社健康版五月一日报道（作者David Douglas）Am J Epidemiol 2008;167:867-874：据挪威的研究人员在美国流行病学期刊的四月份评论上报道, 在妊娠之前或之中补充叶酸和其他维生素可降低胎盘早剥的危险性。Bergen大学的Roy M. Nilsen博士和他的同事们研究了在挪威记录的1999至2004年之间的超过280，000名独生子分娩资料。共有1070名发生胎盘早剥（0.38%）。补充或者不补充多种维生素中，在妊娠前或之中补充叶酸发生早剥的概率为36.4%， 而未补充叶酸早剥的概率为44.4%。相比于未用任何补充者，使用补充物的校正优势比为0.74。而对于单用叶酸者， 优势比为0.81. 对于多种维生素应用者，其为0.72. 最好的效果见于两种补充物均用者（校正优势比，0.68 ）。一旦这样的结果在介入研究中被证实，Nilsen博士在路透社健康版评论，“这将会使当前的建议得以流行蔓延，即通过在妊娠之前及妊娠早期确保足够量的叶酸摄入来预防神经管缺陷。 singleton deliveries：独生子女 可能还是：单胎生育 更明确
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作者:admin@医学,生命科学 2010-10-05 05:11
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