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【medical-news】大麻可减轻艾滋病相关的神经痛
——Study Shows Smoking Pot Provides Pain Relief From HIV-Related Neuropathy
Aug. 6, 2008 -- Smoking pot may help relieve pain in patients with HIV-related neuropathy, a form of nerve damage that leads to burning and tingling sensations, which can be hard to treat with traditional medications.
"Neuropathy is a chronic and significant problem in HIV patients as there are few existing treatments that offer adequate pain management," researcher Ronald J. Ellis, MD, PhD, associate professor of neurosciences at the University of California, San Diego School of Medicine, says in a news release.
Ellis and colleagues compared medical marijuana to a placebo (fake drug) in 28 patients with HIV-related neuropathic pain that was not adequately controlled by pain medications, including opioids.
The team randomly assigned each participant to smoke either medical marijuana (cannabis) or a cigarette that resembled marijuana but did not contain the drug's active chemical, THC. The National Institute on Drug Abuse supplied both products.
The participants smoked the material four times a day for five straight days, then abstained for two weeks, and then followed the same experiment again. Each person also continued to take prescribed painkillers during the trial.
Smoking the pot provided much greater pain relief than smoking the placebo. Forty-six percent of participants had clinically meaningful pain relief with pot compared to 18% with placebo. Pain relief varied from "strong" to "mild to moderate."
The researchers say that medical marijuana significantly reduces HIV-related neuropathic pain when added to the patient's already-prescribed pain management regimen and may be an "effective option for pain relief" in those whose pain is not controlled with current medications.
The findings, which appear online in the journal Neuropsychopharmacology, add to a growing body of evidence that shows that medical marijuana can be a potent painkiller for patients with neuropathy. However, the substance can have a negative impact on certain mental skills.
Ellis' team also warns that long-term smoking of cannabis can cause lung problems. Alternative delivery methods are approved in Great Britain and Canada and are being considered by the U.S., according to background information in the journal article.
http://www.webmd.com/hiv-aids/news/20080805/marijuana-eases-nerve-pain-due-to-hiv
相关阅读：安慰剂试验中吸食大麻者与艾滋病相关的脚痛减轻
http://www.dxy.cn/bbs/post/view?bid=116&id=8301632&sty=3&keywords=%B4%F3%C2%E9+HIV 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 Marijuana Eases Nerve Pain Due to HIV
——Study Shows Smoking Pot Provides Pain Relief From HIV-Related
Neuropathy
大麻可减轻艾滋病相关的神经痛
Aug. 6, 2008 -- Smoking pot may help relieve pain in patients with HIV-related neuropathy, a form of nerve damage that leads to burning and tingling sensations, which can be hard to treat with traditional medications.
2008年8月6日——吸食大麻可能帮助减轻艾滋病相关的神经疾病，这是一种导致烧灼和刺痛感觉的神经损伤，传统的药物治疗很难奏效。
"Neuropathy is a chronic and significant problem in HIV patients as there are few existing treatments that offer adequate pain management," researcher Ronald J. Ellis, MD, PhD, associate professor of neurosciences at the University of California, San Diego School of Medicine, says in a news release.
加州大学圣迭戈医学院神经科学副教授、医学博士、哲学博士Ronald J. Ellis在一次新闻发布会上说：“神经痛是艾滋病人一种慢性的、值得重视的疾病，目前几乎没有能充分止痛的治疗方法。”
Ellis and colleagues compared medical marijuana to a placebo (fake drug) in 28 patients with HIV-related neuropathic pain that was not adequately controlled by pain medications, including opioids.
Ellis和同事们比较了医用大麻和对照组（安慰剂药物）在治疗药物（包括阿片）止痛控制不好的艾滋病相关神经痛的疗效。
The team randomly assigned each participant to smoke either medical marijuana (cannabis) or a cigarette that resembled marijuana but did not contain the drug's active chemical, THC. The National Institute on Drug Abuse supplied both products.
研究小组对参与者进行了随机分组，一组吸食医用大麻，另一组吸食含大麻有效成分四氢大麻酚的类似品，两种药品均由国立药物滥用研究所提供。
The participants smoked the material four times a day for five straight days, then abstained for two weeks, and then followed the same experiment again. Each person also continued to take prescribed painkillers during the trial.
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作者:admin@医学,生命科学 2011-03-10 17:14
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