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【bio-news】CELL BIOLOGY: Cases of Mistaken Identity
For decades, biologists working with contaminated or misidentified cell lines have wasted time and money and produced spurious results; journals and funding agencies say it's not their job to solve this problem
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As journals wrestle with the problems posed by cell line mix-ups--Reynolds goes so far as to estimate that journals would have to retract 35% to 40% of their previously published cell biology papers to weed out invalid data--some organizations are trying to help in different ways. The Society for In Vitro Biology will hold a symposium at its 2007 annual meeting in which Yvonne Reid of ATCC will talk about how contamination can be prevented. Nardone, Masters, and Joseph Perrone of ATCC are also organizing a conference to discuss standards and guidelines that could lead to profession-wide compliance for authentication. And ATCC, which has for decades sold lines overtaken by HeLa, recently decided to stop routinely distributing the lines, except for special requests from researchers. But these efforts will have limited effect, says Nardone, if journals and grant-awarding agencies won't mandate cell line authentication. What biologists need, he concludes, is a "stick saying that if you don't do this, there will be a consequence." When Walter Nelson-Rees first raised the alarm about cell line contamination in the 1970s, it threw the research community into a frenzy. Now other scientists are taking up his fight
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【进展】CELL BIOLOGY: When 60 Lines Don't Add Up
http://www.dxy.cn/bbs/post/view?bid=87&id=8317009&sty=1
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作者:admin@医学,生命科学 2011-03-06 17:19
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