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【NEJM】中国人吸烟所导致的死亡
ABSTRACT
Background Smoking is a risk factor for many diseases and has been increasingly prevalent in economically developing regions of the world. We aimed to estimate the number of deaths attributable to smoking in China.
Methods We conducted a large, prospective cohort study in a nationally representative sample of 169,871 Chinese adults who were 40 years of age or older. Investigators for the China National Hypertension Survey collected data on smoking and other risk factors at a baseline examination in 1991 using a standard protocol. Follow-up evaluation was conducted in 1999 and 2000, with a response rate of 93.4%. We used multivariable-adjusted relative risk, prevalence of smoking, mortality, and population size in each age group, stratified according to sex, to calculate the number of deaths attributable to smoking in 2005.
Results There was a significant, dose–response association between pack-years smoked and death from any cause in both men and women after adjustment for multiple risk factors (P<0.001 for trend). We estimated that in 2005, a total of 673,000 deaths (95% confidence interval [CI], 564,700 to 781,400) were attributable to smoking in China: 538,200 (95% CI, 455,800 to 620,600) among men and 134,800 (95% CI, 108,900 to 160,800) among women. The leading causes of smoking-related deaths were as follows: cancer, 268,200 (95% CI, 214,500 to 321,900); cardiovascular disease, 146,200 (95% CI, 79,200 to 213,100); and respiratory disease, 66,800 (95% CI, 20,300 to 113,300).
Conclusions Our study documents that smoking is a major risk factor for mortality in China. Continued strengthening of national programs and initiatives for smoking prevention and cessation is needed to reduce smoking-related deaths in China.
http://content.nejm.org/cgi/content/full/360/2/150 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领 Mortality Attributable to Smoking in China
中国因吸烟引起的死亡
ABSTRACT
摘要：
Background Smoking is a risk factor for many diseases and has been increasingly prevalent in economically developing regions of the world. We aimed to estimate the number of deaths attributable to smoking in China.
背景：在发展中国家，吸烟是很多疾病的风险因子，但是在世界上发展中地区中，吸烟却正在日益广泛。我们研究的目的是对中国因吸烟引起的死亡人数进行评估。
Methods We conducted a large, prospective cohort study in a nationally representative sample of 169,871 Chinese adults who were 40 years of age or older. Investigators for the China National Hypertension Survey collected data on smoking and other risk factors at a baseline examination 中国因吸烟引起的死亡
摘要：
背景：在发展中国家，吸烟是很多疾病的风险因子，但是在世界上发展中地区中，吸烟却正在日益广泛。我们研究的目的是对中国因吸烟引起的死亡人数进行评估。
方法：我们进行了一项大规模的深入群组研究，样本来自于全国范围内具有代表性的169871名中国成人，年龄大于40岁。中国国家高血压勘查机构在1991年用标准程序在基线检查水平上收集了吸烟以及其他风险因子的数据。在1999和2000年对上述人员进行了跟踪率为93.4%的评估。我们在2005年用多变量调整相对风险，吸烟普遍性，死亡率，每个年龄组的人群大小，根据性别分组，来计算因吸烟导致的死亡人数。
结果：我们发现，在多种风险因素调整之后，男性和女性被调查样本中，年吸烟包数和因各种原因引发的死亡数之间均有显著的剂量反应联系（P<0.001）。根据我们的估算，2005年中，中国共有673000例死亡人数是由吸烟引起的（置信区间95%，564700到781400），其中男性538200例（置信区间95%，455800到620600），女性134800例（置信区间95%，108900到160800）。和吸烟相关的主要致死原因分别是：癌症268200例（置信区间95%，214500到321900）；心血管疾病146200例（置信区间95%，79200到213100）；呼吸系统疾病66800例（置信区间95%，20300到113300）。
结论：我们的研究结果表明：在中国，吸烟是死亡率的主要风险因素。继续加强国家对禁止吸烟的项目和主动权对于减少中国吸烟相关死亡数目是必要的。 危言耸听！
哥伦比亚号航天飞机坠毁与全球华人欢度春节燃放鞭炮在时间上密切相关！实际上不是放鞭炮炸毁的！
要关注的因素还很多！到现在为止请问哪种疾病是吸烟所致，那个死亡病例是吸烟所致？
莫须有！医学领域里的冤案太多了！ 那也不能就肯定吸烟吧！！
sdytzyc wrote:
危言耸听！
哥伦比亚号航天飞机坠毁与全球华人欢度春节燃放鞭炮在时间上密切相关！实际上不是放鞭炮炸毁的！阅读本文的人还阅读：
作者:admin@医学,生命科学 2011-06-15 05:11
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