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【科普】补充VE增加嗜烟者罹患结核风险
NEW YORK (Reuters Health) - The use of vitamin E supplements appears to increase the risk of tuberculosis in some middle-aged smokers, according to a study in the British Journal of Nutrition.
In the overall analysis, vitamin E use did not affect the odds of tuberculosis in smokers. In people who smoked at least 20 cigarettes per day and consumed diets high in vitamin C, however, vitamin E supplements more than doubled the risk.
Vitamin E is a widely used dietary supplement believed to enhance immune function, note authors Dr. Harri Hemila and Dr. Jaakko Kaprio. However, trials in human subjects have shown unpredictable effects of vitamin E on various infectious diseases.
To examine the impact of vitamin E use on the risk of tuberculosis, the two researchers from the University of Helsinki in Finland analyzed data from the ATBC (Alpha-Tocopherol, Beta-Carotene Cancer Prevention) Study.
The study participants were 29,023 male smokers, ages 50 to 69 years, who were randomly assigned to take daily supplements containing vitamin E, beta-carotene, vitamin E plus beta-carotene, or inactive placebo.
During a follow-up period of around 6 years, 174 cases of tuberculosis were diagnosed. Overall, neither vitamin E nor beta-carotene supplements affected the risk of tuberculosis.
However, as noted, the combination of smoking 20 or more cigarettes per day and consuming a diet rich in vitamin C and vitamin E supplements more than doubled the risk of tuberculosis. Further analysis showed that the increased risk was restricted to the first year after vitamin E supplementation began.
"Although vitamin E may be beneficial in restricted population groups, those groups are poorly defined so far," Hemila and Kaprio point out.
"The consumption of vitamin E supplements by the general population should be discouraged because there is evidence of harm for some people," they conclude.
http://www.reuters.com/article/healthNews/idUSTON60332720080226
screen.width-333)this.width=screen.width-333" width=328 height=254 title="Click to view full 新图片.JPG (328 X 254)" border=0 align=absmiddle> 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 Vitamin E use may raise tuberculosis risk in heavy smokers
嗜烟者服用维生素E可能会增加患结核的风险
NEW YORK (Reuters Health) - The use of vitamin E supplements appears to increase the risk of tuberculosis in some middle-aged smokers, according to a study in the British Journal of Nutrition.
纽约（路透社健康信息）-----根据英国营养杂志报道的一个研究认为，补充维生素E可能会增加一些中年吸烟者患结核的风险。
In the overall analysis, vitamin E use did not affect the odds of tuberculosis in smokers. In people who smoked at least 20 cigarettes per day and consumed diets high in vitamin C, however, vitamin E supplements more than doubled the risk.
总的来说，补充维生素E不影响吸烟者患结核的机会。然而，对于每天吸烟至少20支以上，进食含维生素C丰富的食物、补充维生素E则会增加超过2倍的患结核风险。
Vitamin E is a widely used dietary supplement believed to enhance immune function, note authors Dr. Harri Hemila and Dr. Jaakko Kaprio. However, trials in human subjects have shown unpredictable effects of vitamin E on various infectious diseases.
Harri Hemila和Jaakko Kaprio博士说，维生素E被认为可以提高免疫力而被广泛使用。然而，临床试验显示维生素E对多种感染性疾病产生不可预测的影响。
To examine the impact of vitamin E use on the risk of tuberculosis, the two researchers from the University of Helsinki in Finland analyzed data from the ATBC (Alpha-Tocopherol, Beta-Carotene Cancer Prevention) Study.
来自芬兰赫尔辛基大学的两位研究人员，为了检测维生素E使用对患结核的风险，分析了从ATBS(Alpha-Tocopherol, Beta-Carotene Cancer Prevention)研究获得的数据。
The study participants were 29,023 male smokers, ages 50 to 69 years, who were randomly assigned to take daily supplements containing vitamin E, beta-carotene, vitamin E plus beta-carotene, or inactive placebo.
被研究的对象有29023名男性吸烟者，年龄从50到69对，他们被随机分到每天补充维生素E组，每天补充维生素E+beta胡萝卜素组，和补充安慰剂组。
During a follow-up period of around 6 years, 174 cases of tuberculosis were diagnosed. Overall, neither vitamin E nor beta-carotene supplements affected the risk of tuberculosis.
在长达6年的随访中，总共出现了174例结核病例，维生素E和beta胡萝卜素都没有影响患结核的风险。
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作者:admin@医学,生命科学 2011-03-04 01:29
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