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【medical-news】腹型肥胖增加老年痴呆风险

March 26, 2008, 4:44 pm

Is Belly Fat Bad for Your Brain?

Posted by Jacob Goldstein



People who have a big belly during middle age are more likely to develop dementia in old age, researchers are reporting. It’s another sign that the belly is an especially bad place to be fat.

Scientists at Kaiser looked at measurements taken from more than 6,500 people between 1964 and 1973, when the patients were between the ages of 40 and 45. Then the researchers looked at the patients’ health records during the years 2004-2006, to see which ones had been diagnosed with dementia.

Among those whose belly sizes were in the largest 20%, 3.2% developed dementia; the rate was 2.2% for those with the smallest bellies.

After adjusting for variables such as education, diabetes and heart disease, the researchers concluded that the risk of developing dementia was 2.7 times higher for those with the largest bellies, compared with those whose bellies were smallest. The study was published today in the journal Neurology.

A study like this can’t clearly prove that the belly fat is contributing to dementia — there may be some unknown factor that makes people more likely to have a lot of belly fat and more likely to develop dementia. But it’s been clear for a while that the way in which people are fat has important health consequences, and belly fat is especially bad.

It’s a key marker for the cluster of risk factors known as metabolic syndrome, and it sharply increases the risk of heart disease and diabetes. It’s not entirely clear why belly fat is so bad. But it does tend to be easier to shed than fat stored other places, Rachel Whitmer, the lead author, told the WSJ. “This is not a stubborn fat,” she said. “It is a toxic fat.”

http://blogs.wsj.com/health/2008/03/26/is-belly-fat-bad-for-your-brain/?mod=WSJBlog March 26, 2008, 4:44 pm

Is Belly Fat Bad for Your Brain?

腹部脂肪对大脑有害?

People who have a big belly during middle age are more likely to develop dementia in old age, researchers are reporting. It’s another sign that the belly is an especially bad place to be fat.

研究人员报道,中年发福的人,到了老年发生痴呆症的可能性较大。这是腹部脂肪对人体健康不利的又一个证据。

Scientists at Kaiser looked at measurements taken from more than 6,500 people between 1964 and 1973, when the patients were between the ages of 40 and 45. Then the researchers looked at the patients’ health

records during the years 2004-2006, to see which ones had been diagnosed with dementia.

凯塞研究机构的科学家在1964年~1973年对年龄40~45岁的6500多人进行测量。然后在2004年~2006年分析患者的健康记录,看看哪些人已被诊断为老年痴呆症。

Among those whose belly sizes were in the largest 20%, 3.2% developed dementia; the rate was 2.2% for those with the smallest bellies.

腹围最大的20%受试者痴呆发生率为3.2 %,而那些腹围最小的受试者痴呆的发生率为2.2%。

After adjusting for variables such as education, diabetes and heart disease, the researchers concluded that the risk of developing dementia was 2.7 times higher for those with the largest bellies, compared

with those whose bellies were smallest. The study was published today in the journal Neurology.

在调整了教育程度、糖尿病和心脏病等相关变量后,研究者们得出结论,腹围最大组发展为痴呆症的风险与腹围最小组相比增加2.7倍。这项研究发表在《神经病学》杂志。

A study like this can’t clearly prove that the belly fat is contributing to dementia — there may be some unknown factor that makes people more likely to have a lot of belly fat and more likely to develop

dementia. But it’s been clear for a while that the way in which people are fat has important health consequences, and belly fat is especially bad.

这项研究尚不能完全证明腹部脂肪促成了老年痴呆症——可能有一些未知因素,导致人们更易发展为腹型肥胖,更易于发生痴呆症。但关于肥胖对健康的重要影响已经非常明了,特别是腹部脂肪尤其有害。

It’s a key marker for the cluster of risk factors known as metabolic syndrome, and it sharply increases the risk of heart disease and diabetes. It’s not entirely clear why belly fat is so bad. But it does

tend to be easier to shed than fat stored other places, Rachel Whitmer, the lead author, told the WSJ. “This is not a stubborn fat,” she said. “It is a toxic fat.”

腹型肥胖是代谢综合征一系列危险因素的关键标记,它大大增加了患心脏病和糖尿病的风险。目前还没有完全搞清楚为什么腹部脂肪有如此多不利影响,但脂肪在腹部比在身体其他部位更容易堆积,该研究的主要作者Rachel Whitmer接受华尔街日报采访时说, "这不是一种顽固的脂肪,而是一种有害的脂肪" 。

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作者:admin@医学,生命科学    2011-03-04 01:28
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