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【medical-news】新型痴呆筛查工具
New research finds Saint Louis University tool is more sensitive
ST. LOUIS -- A screening tool for dementia developed by Saint Louis University geriatricians appears to work better in identifying mild cognitive problems in the elderly than the commonly used Mini Mental Status Examination, according to a new study.
Physicians routinely administer the Mini Mental Status Examination (MMSE) to patients who they believe may have Alzheimer's disease. Both the MMSE and SLU's screening tool ? the Saint Louis University Mental Status Examination (SLUMS) ? indicate to doctors when they should pursue further testing in diagnosing dementia.
"This early detection of mild neurocognitive disorder by the SLUMS offers the opportunity for the clinicians to begin early treatment as it becomes available," says Syed Tariq, M.D., lead author and associate professor of geriatric medicine at Saint Louis University.
John Morley, M.D., director of the division of geriatric medicine at Saint Louis University, created the SLUMS to screen more educated patients and to detect early cognitive problems.
"There are potential treatments available and they slow down the progression of the disease," says Morley, who is a coinvestigator. "The earlier you treat, the better people seem to do. But families go through denial and sometimes miss diagnosing dementia until its symptoms are no longer mild."
The researchers found the new screening tool developed by SLU detects early cognitive problems missed by the MMSE.
"The Mini Mental Status Examination has limitations, especially with regard to its use in more educated patients and as a screen for mild neurocognitive disorder," Tariq says.
It takes a clinician about seven minutes to administer the SLUMS, which supplements the Mini Mental Status Examination by asking patients to perform tasks such as doing simple math computations, naming animals, recalling facts and drawing the hands on a clock.
Both screening tools work at detecting dementia, the research found.
"SLUMS has the advantage in that it can help the clinician identify patients with mild neurocognitive disorder on the initial visit compared to MMSE, which requires a follow up screening," Tariq says.
Saint Louis University researchers used both screening tools to test 705 men who were at least 60 and treated at the Geriatric Research Education Clinical Center, Veterans Administration Hospitals in St. Louis in 2003. They found that while both tools detected dementia, only the SLUMS recognized a group of patients as having mild cognitive problems.
The SLUMS, which is free and currently used at many Veterans Administration hospitals, is available at this link http://medschool.slu.edu/agingsuccessfully/pdfsurveys/slumsexam_05.pdf
The researchers cautioned that neither the SLUMS nor the MMSE screening tools substitute for clinical assessment and neuropsychological testing to diagnose cognitive problems and dementia.
http://www.eurekalert.org/pub_releases/2006-11/slu-nds103006.php 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 New dementia screening tool detects early cognitive problems missed by commonly used test
New research finds Saint Louis University tool is more sensitive 新的痴呆筛查工具能探测出用目前通常使用的方法不能探测出的早期认知功能障碍，新研究发现圣路易斯大学的工具更灵敏。
ST. LOUIS -- A screening tool for dementia developed by Saint Louis University geriatricians appears to work better in identifying mild cognitive problems in the elderly than the commonly used Mini Mental Status Examination, according to a new study. 根据一项新的研究，ST. LOUIS----圣路易斯大学的老年病学专家开发的新痴呆筛选工具，在鉴定老年人轻度认知障碍方面作用比普遍使用的简易智能评估强。
Physicians routinely administer the Mini Mental Status Examination (MMSE) to patients who they believe may have Alzheimer's disease. Both the MMSE and SLU's screening tool ? the Saint Louis University Mental Status Examination (SLUMS) ? indicate to doctors when they should pursue further testing in diagnosing dementia. 医生通常给可能有阿尔茨海默病的病人使用简易智能评估。无论是简易智能评估（MMSE）也好，还是圣路易斯大学的筛选工具----圣路易斯大学的智能评估（SLUMS）都强调医生在确诊老年痴呆病人时，需要进行进一步检测。
"This early detection of mild neurocognitive disorder by the SLUMS offers the opportunity for the clinicians to begin early treatment as it becomes available," says Syed Tariq, M.D., lead author and associate professor of geriatric medicine at Saint Louis University.“通过圣路易斯大学的智能评估检测，可以帮助临床医生对轻度的认知神经失调进行早期的治疗。”医学博士，Syed Tariq表示，他是圣路易斯大学老年病学的副教授。
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作者:admin@医学,生命科学 2010-11-09 05:11
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