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【文摘发布】经组织学证实的肝血管瘤的超声造
Authorsietrich CF, Mertens JC, Braden B, Schuessler G, Ott M, Ignee A.
Resource: Hepatology. 2007 May;45(5):1139-45.
Abstract:
Differentiation of small and atypical hemangiomas from other hepatic masses using imaging methods can be difficult, especially in patients with underlying malignant disease. Therefore, contrast-enhanced ultrasound was assessed in patients with histologically confirmed hemangiomas with respect to contrast-enhancing kinetics and tumor characteristics. In 58 patients with indeterminate hepatic lesions demonstrated with at least 2 imaging methods (ultrasound/computed tomography/magnetic resonance imaging), ultrasound-guided liver biopsy revealed hemangioma. In all patients a hepatic neoplasm had been suspected because of underlying malignant disease (n = 41), liver cirrhosis (n = 15), or growth of the lesion (n = 2). All patients underwent nonlinear, low mechanical index real-time contrast-enhanced ultrasound scanning with bolus injections of SonoVue. Peripheral nodular arterial enhancement was detected in 43 patients (74%), whereas the typical metastatic peripheral rim-like enhancement was not observed at all. Strong homogenous arterial enhancement was found in 9 of 58 (16%) patients. In 6 patients (10%), the arterial contrast enhancement pattern could not be determined because of the very small size of the lesions or fibrotic nodules. Forty-five (78%) of the hemangiomas showed homogenous centripetal filling within 180 seconds. Conclusion: Contrast-enhanced ultrasound demonstrates typical hemangioma imaging characteristics, that is, peripheral nodular contrast enhancement and iris-diaphragm sign in a high percentage of patients with undetermined lesions. This technique may therefore improve noninvasive functional characterization and differentiation of hemangiomas. (HEPATOLOGY 2007;45:1139-1145.).
PMID: 17464990 本人已认领该文编译，24小时后若未提交译文，请其他战友自由认领。 Title:Contrast-enhanced ultrasound of histologically proven liver hemangiomas.
经组织学证实的肝血管瘤的超声造影
Authors：Ietrich CF, Mertens JC, Braden B, Schuessler G, Ott M, Ignee A
Resource: Hepatology. 2007 May;45(5):1139-45.
来源：《肝脏病》.2007 May；45（5）：1139-45.
Abstract:摘要
Differentiation of small and atypical hemangiomas from other hepatic masses using imaging methods can be difficult, especially in patients with underlying malignant disease.
利用影像学方法来鉴别小的不典型肝血管瘤与其它肝脏肿块是很困难的，尤其是在一些本身存在潜在的恶性疾病的病人。
Therefore, contrast-enhanced ultrasound was assessed in patients with histologically confirmed hemangiomas with respect to contrast-enhancing kinetics and tumor characteristics.
因此，人们评估了超声造影在组织学证实的肝血管瘤患者中的作用，以了解其动态增强表现与肿瘤特点之间的关系。
In 58 patients with indeterminate hepatic lesions demonstrated with at least 2 imaging methods (ultrasound/computed tomography/magnetic resonance imaging), ultrasound-guided liver biopsy revealed hemangioma.
在58个病人中，至少两种影像学方法（超声/CT/MRI）均表明其存在不确定的肝脏病变，而超声引导的肝穿刺活检证实为肝血管瘤。
In all patients a hepatic neoplasm had been suspected because of underlying malignant disease (n = 41), liver cirrhosis (n = 15), or growth of the lesion (n = 2).
在所有病人中，因潜在的恶性疾病（41例）、肝硬化（15例）、病变增大（2例）均曾被怀疑为患有肝脏肿瘤。
All patients underwent nonlinear, low mechanical index real-time contrast-enhanced ultrasound scanning with bolus injections of SonoVue.
所有病人均用声诺维（SonoVue）静脉团注，接受非线性、低机械指数实时增强超声扫描。
Peripheral nodular arterial enhancement was detected in 43 patients (74%), whereas the typical metastatic peripheral rim-like enhancement was not observed at all.
动脉期周围结节状增强在43个（74%）病人中被观察到，而典型的转移性周边轮状强化并没有观察到。
Strong homogenous arterial enhancement was found in 9 of 58 (16%) patients. In 6 patients (10%), the arterial contrast enhancement pattern could not be determined because of the very small size of the lesions or fibrotic nodules.
58个病人中的9个（16%）观察到强烈的动脉期均质强化。在6例（10%）病人中，由于病变很小或纤维结节的原因，动脉期增强模式不能确定。
Forty-five (78%) of the hemangiomas showed homogenous centripetal filling within 180 seconds.
45例（78%）肝血管瘤在180秒内表现为均质的向心性填充。
Conclusion: Contrast-enhanced ultrasound demonstrates typical hemangioma imaging characteristics, that is, peripheral nodular contrast enhancement and iris-diaphragm sign in a high percentage of patients with undetermined lesions.
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作者:admin@医学,生命科学 2010-10-02 05:11
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