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【medical-news】宾夕法尼亚州检测终止房颤的新工
New tool being tested at Penn to halt recurrence of atrial fibrillation
Benefits could include shorter procedure time and improved effectiveness
(PHILADELPHIA) -- Clinical researchers at the University of Pennsylvania Health System are starting a trial utilizing a new mechanism to treat the heart when its electrical pulses essentially short-circuit, referred to as atrial fibrillation (A-Fib).
The biggest problem physicians run into with current therapies to cope with electrical rhythmic pumping problems in the heart, namely pulmonary vein isolation procedures, is that up until now, they抳e had to deliver the energy bursts to the tissue in a dot-by-dot catheter ablation procedure around the veins, almost like a string of pearls. "That can cause swelling, and when that swelling goes down, you may still have viable tissue left behind, gaps, where the electricity can still conduct itself or get through," explains David Callans, MD, director of the electrophysiology laboratory at the Hospital of the University of Pennsylvania and principal investigator of this study. "Now we have a mechanism to construct this barricade of lesions, to do an entire circular ablation, minimizing the potential for gaps behind in the pulmonary veins."
Cardiac electrophysiologists at Penn are now using a high intensity focused ultrasound (HIFU) ablation system. It抯 the first to deliver energy bursts forward in a complete circle, all at once, from outside of the vein. This invasive procedure is done in the lab with balloon catheters while the patient is awake but sedated.
Electrophysiologists use ablation procedures (involving intense heat on the area of the heart causing the rhythmic pumping problems) to turn pulmonary vein tissue into scar tissue so that it can no longer conduct electricity. When this is done in several locations, it can effectively stop the symptoms of atrial fibrillation, which affects as many as five million Americans. "Since this new system sits outside of the vein, and delivers energy forward rather than immediately around it, there is no damage to the inside of the vein. This maintains a normal blood flow. Plus, this new system could shorten the ablation procedure time which currently takes about four hours," adds Callans.
Penn Medicine, which has one of the largest cardiac electrophysiology programs in the country, has been doing atrial fibrillation ablation procedures for the last several years. Callans states, "Ablation is definitely the future for treatment of atrial fibrillation. Everything else we currently use to treat A-Fib is flawed. So the ablation procedure itself has to improve, become more effective and safer. And one way we can do this is on the technology front by developing better tools. This trial may be a big part of that." 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 New tool being tested at Penn to halt recurrence of atrial fibrillation
Benefits could include shorter procedure time and improved effectiveness
宾夕法尼亚州正在试验中止房颤的新工具
可能缩短治疗时间，提高疗效
(PHILADELPHIA) -- Clinical researchers at the University of Pennsylvania Health System are starting a trial utilizing a new mechanism to treat the heart when its electrical pulses essentially short-circuit, referred to as atrial fibrillation (A-Fib).
费城消息：宾夕法尼亚大学健康系统的临床研究者正在进行治疗房颤的新方法的临床试验。房颤是由心肌电冲动大部分经短路折返传导而引起的。
The biggest problem physicians run into with current therapies to cope with electrical rhythmic pumping problems in the heart, namely pulmonary vein isolation procedures, is that up until now, they抳e had to deliver the energy bursts to the tissue in a dot-by-dot catheter ablation procedure around the veins, almost like a string of pearls. "That can cause swelling, and when that swelling goes down, you may still have viable tissue left behind, gaps, where the electricity can still conduct itself or get through," explains David Callans, MD, director of the electrophysiology laboratory at the Hospital of the University of Pennsylvania and principal investigator of this study. "Now we have a mechanism to construct this barricade of lesions, to do an entire circular ablation, minimizing the potential for gaps behind in the pulmonary veins."
主要研究者，宾州大学医院电生理实验室的主任，David Callans说，临床医生在运用目前的方法（肺静脉隔离术）治疗房颤的最大的问题是，他们必需把能量冲动一个点一个点地传到肺静脉周围的组织中以进行导管消融，这些点象一串珍珠一样，“这可能导致局部组织肿胀，当肿胀消失后，原先的短路依然存在，还能传导电冲动”，“我们的方法是在肺静脉周围构建一个环状消融损伤屏障，尽量减小肺静脉后方潜在的空隙。”
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作者:admin@医学,生命科学 2011-04-06 17:11
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