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【文摘发布】临床 IA 期非小细胞肺癌行肺段切除
J Thorac Cardiovasc Surg 2007;133:780-785
Objective: Intraoperative frozen section examination of sentinel lymph nodes was conducted to determine the final indication for segmentectomy for clinical T1 N0 M0 non–small cell lung cancer.
Methods: Between April 2005 and July 2006, 52 patients with clinical T1 N0 M0 non–small cell lung cancer were prospectively treated by segmentectomy with sentinel node identification. The day before surgery, technetium-99m tin colloid was injected into the peritumoral region. After segmentectomy and lymph node dissection, sentinel nodes identified by measuring radioactive tracer uptake were examined for intraoperative frozen sections, which were serially cut 2 to 3 mm in thickness. When sentinel node metastasis was observed, segmentectomy was converted to lobectomy.
Results: Sentinel nodes were identified in 43 (83%) patients. The average number of sentinel nodes was 1.6 ± 0.9 (range: 1–5) per patient. Of 3 patients with metastatic sentinel lymph nodes, 2 underwent lobectomy and 1 larger segmentectomy. None of the other 40 patients had metastatic sentinel lymph nodes and therefore they were treated with segmentectomy. Pathologic staging with permanent sections was N0 in all of the 40 patients. On the other hand, in 9 patients whose sentinel nodes could not be identified, intraoperative frozen sections were required for 5.4 ± 2.3 lymph nodes, which was significantly more than 1.6 ± 0.9 in the 43 patients with sentinel node identification (P < .001).
Conclusion: Sentinel node identification is useful to determine the final indication of segmentectomy for clinical T1 N0 M0 non–small cell lung cancer by targeting the lymph nodes needed for intraoperative frozen section diagnosis.
http://jtcs.ctsnetjournals.org/cgi/content/abstract/133/3/780[url][/url] 本人认领，48小时未提交，请其他战友自由认领 Sentinel node navigation segmentectomy for clinical stage IA non–small cell lung cancer
临床分期为IA期的非小细胞肺癌哨位淋巴结活检指导进行肺段切除术
J Thorac Cardiovasc Surg 2007;133:780-785
胸心血管外科杂志2007;133:780-785
Objective: Intraoperative frozen section examination of sentinel lymph nodes was conducted to determine the final indication for segmentectomy for clinical T1 N0 M0 non–small cell lung cancer.
目的：对于临床分期T1N0M0的非小细胞肺癌病人术中行哨位淋巴结快速冰冻切片检查以最终指导肺段切除术。
Methods: Between April 2005 and July 2006, 52 patients with clinical T1 N0 M0 non–small cell lung cancer were prospectively treated by segmentectomy with sentinel node identification. The day before surgery, technetium-99m tin colloid was injected into the peritumoral region. After segmentectomy and lymph node dissection, sentinel nodes identified by measuring radioactive tracer uptake were examined for intraoperative frozen sections, which were serially cut 2 to 3 mm in thickness. When sentinel node metastasis was observed, segmentectomy was converted to lobectomy.
方法：在2005年4月至2006年7月间，52例临床分期T1N0M0的非小细胞肺癌病人应用哨位淋巴结检查前瞻性指导后应用肺段切除术。术前1天，同位素锝-99胶体制剂（tin colloid，译为胶体制剂妥当否?请高手指正！谢谢！ 临床分期为IA期的非小细胞肺癌哨位淋巴结活检指导进行肺段切除术
胸心血管外科杂志2007;133:780-785
目的：对于临床分期T1N0M0的非小细胞肺癌病人术中行哨位淋巴结快速冰冻切片检查以最终指导肺段切除术。
方法：在2005年4月至2006年7月间，52例临床分期T1N0M0的非小细胞肺癌病人应用哨位淋巴结检查前瞻性指导后应用肺段切除术。术前1天将同位素锝-99胶体制剂（tin colloid，译为胶体制剂妥当否？请高手指正，谢谢！ Objective: Intraoperative frozen section examination of sentinel lymph nodes was conducted to determine the final indication for segmentectomy for clinical T1 N0 M0 non–small cell lung cancer.
目的：对于临床分期T1N0M0的非小细胞肺癌病人术中行哨位淋巴结快速冰冻切片检查以最终指导肺段切除术。
修改为：
目的：明确术中前哨淋巴结冰冻切片检查作为临床T1N0M0期非小细胞肺癌病人行肺段切除术最终指征的意义。
Methods: Between April 2005 and July 2006, 52 patients with clinical T1 N0 M0 non–small cell lung cancer were prospectively treated by segmentectomy with sentinel node identification. The day before surgery, technetium-99m tin colloid was injected into the peritumoral region. After segmentectomy and lymph node dissection, sentinel nodes identified by measuring radioactive tracer uptake were examined for intraoperative frozen sections, which were serially cut 2 to 3 mm in thickness. When sentinel node metastasis was observed, segmentectomy was converted to lobectomy.
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作者:admin@医学,生命科学 2010-10-21 05:11
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