主页 > 医学讨论 >
【文摘发布】香港威尔士亲王医院腹膜透析患者
AJKD Volume 49, Issue 5, Pages 682-692 (May 2007)
Nutrient Intake During Peritoneal Dialysis at the Prince of Wales Hospital in Hong Kong
Angela Yee-Moon Wang, MD, FRCP1⁎, Mandy Man-Mei Sea, BSc2, Kenway Ng, BSc1, Mandy Kwan, BSc1, Siu-Fai Lui, FRCP1, Jean Woo, FRCP2
Background
Individuals undergoing peritoneal dialysis are at increased risk of developing cardiac disease and malnutrition.
Study Design
A cross-sectional survey.
Settings and Participants
249 Chinese continuous ambulatory peritoneal dialysis (CAPD) patients were recruited from the Prince of Wales Hospital in Hong Kong. Another 249 age- and sex-matched controls were recruited from an archive of 1,010 individuals with known food frequency questionnaire (FFQ) data.
Objective
To compare the dietary intake pattern of CAPD patients with controls and evaluate its association with background cardiac disease.
Outcomes and Measurements
Intake of different nutrients was estimated by using a 7-day FFQ.
Results
Intake of all nutrients was lower in CAPD patients than controls, with resulting lower overall energy intake. Nutrient intake was decreased further in CAPD patients with background cardiac disease, which corresponded to worse nutritional status. Controlling for age, male sex, body weight, diabetes mellitus, dialysis therapy duration, residual renal function, peritoneal dialysis urea clearance, and Charlson Comorbidity Index score, background cardiac disease was associated independently with less intake of energy and most macronutrients and micronutrients. However, the association between background cardiac disease and energy and most nutrient intake was decreased or even lost when additional adjustment was made for C-reactive protein and serum albumin levels.
Limitations
An FFQ is limited in that nutrient quantitation is not exact and may be underestimated as a result of underreporting by patients. CAPD patients were compared with a control group without cardiovascular disease ascertainment that did not include subjects with diabetes.
Conclusions
Chinese CAPD patients had significantly lower nutrient intake than age- and sex-matched controls. The association between cardiac disease and lower dietary macronutrient and micronutrient intake in CAPD patients was mediated in part through systemic inflammation, which also was associated with more malnutrition. More attention should be focused on improving the intake pattern of Chinese CAPD patients. 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 AJKD Volume 49, Issue 5, Pages 682-692 (May 2007)
Nutrient Intake During Peritoneal Dialysis at the Prince of Wales Hospital in Hong Kong
香港威尔士亲王医院腹膜透析患者的营养摄入状况
Angela Yee-Moon Wang, MD, FRCP1⁎, Mandy Man-Mei Sea, BSc2, Kenway Ng, BSc1, Mandy Kwan, BSc1, Siu-Fai Lui, FRCP1, Jean Woo, FRCP2
Background 背景
Individuals undergoing peritoneal dialysis are at increased risk of developing cardiac disease and malnutrition.腹膜透析可以增加患者发生心脏病和营养不良的风险
Study Design实验设计
A cross-sectional survey.一个具有代表性的调查研究
Settings and Participants试验设计和试验人员
249 Chinese continuous ambulatory peritoneal dialysis (CAPD) patients were recruited from the Prince of Wales Hospital in Hong Kong. Another 249 age- and sex-matched controls were recruited from an archive of 1,010 individuals with known food frequency questionnaire (FFQ) data. 香港威尔士亲王医院招募了249名持续性不卧床腹膜透析的中国籍患者，另外249名性别匹配的对照组患者由1010名食物摄取频率调查数据的存档中选取。
Objective目标
To compare the dietary intake pattern of CAPD patients with controls and evaluate its association with background cardiac disease. 比较持续性不卧床腹膜透析的中国籍患者的食物摄入和对照组的食物摄入，评估他们的饮食与心血管疾病的关系。
Outcomes and Measurements结果和检测方法
Intake of different nutrients was estimated by using a 7-day FFQ.摄取的不同的营养食物通过7天的食物摄取频率调查进行评估。
Results结果
Intake of all nutrients was lower in CAPD patients than controls, with resulting lower overall energy intake. Nutrient intake was decreased further in CAPD patients with background cardiac disease, which corresponded to worse nutritional status. Controlling for age, male sex, body weight, diabetes mellitus, dialysis therapy duration, residual renal function, peritoneal dialysis urea clearance, and Charlson Comorbidity Index score, background cardiac disease was associated independently with less intake of energy and most macronutrients and micronutrients. However, the association between background cardiac disease and energy and most nutrient intake was decreased or even lost when additional adjustment was made for C-reactive protein and serum albumin levels. 持续性不卧床腹膜透析的中国籍患者的能量摄入量低于对照组，他们摄取的能量低于对照组。据有心脏病的持续性不卧床腹膜透析患者营养摄入量更低，这与他们营养摄入低的程度相一致。对照年龄、性别、体重、糖尿病、透析持续时间、残留的肾功能、腹膜透析的尿素清除率和Charlson Comorbidity评分，我们发现心脏病患者与摄入较少的能量和大量摄入常量营养成分和微量元素。但是当调整C-反应蛋白和白蛋白含量后，心脏疾病和能量、大量营养成分的摄入的相关性下降，甚至不存在。
阅读本文的人还阅读：
作者:admin@医学,生命科学 2010-10-05 18:11
医学,生命科学网