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【medical-news】二尖瓣反流与急性冠脉综合征预后
By David Douglas
NEW YORK (Reuters Health) Dec 28 - The development of functional mitral regurgitation (MR) is associated with a poorer outcome in patients with a first non-ST-segment elevation (NSTSE) acute coronary syndrome (ACS), according to Spanish researchers.
In the November issue of the European Heart Journal, Dr. Leopoldo Perez de Isla and colleagues point out that although the development of MR after myocardial infarction is a frequent complication that has a negative impact on survival. However, relatively little is known about the effect of MR in NSTSEACS patients.
To investigate further, the researchers followed 300 such patients admitted to the coronary care unit of their institution, Hospital Clinico San Carlos, Madrid.
In 42% of the group, MR was detected. Age and left ventricular ejection fraction were the only predictors of its development. There was no independent predictor of in-hospital mortality, although such mortality was significantly higher in the MR group than the non-MR group.
Follow-up for a mean of more than 14 months, showed that long-term outcome was dependent on MR severity. Moreover, this was the sole independent predictor of poor long term prognosis.
Dr. Perez de Isla told Reuters Health that because of these findings, "the presence of mitral regurgitation should be specifically assessed in every patient in this scenario."
In an accompanying editorial, Dr. Luc A. Pierard of University Hospital Sart Tilman, Liege, Belgium agrees and notes that MR should be identified in a variety of cardiac patients.
Doppler echocardiography is the ideal tool, he points out, "as a murmur of MR is rarely heard."
Eur Heart J 2006;27:2655-2660.
http://www.medscape.com/viewarticle/550029 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 Mitral Regurgitation Tied to Poor Acute Coronary Syndrome Outcome
二尖瓣反流与急性冠脉综合征预后不良有关
By David Douglas
大卫-道格琼斯
NEW YORK (Reuters Health) Dec 28 - The development of functional mitral regurgitation (MR) is associated with a poorer outcome in patients with a first non-ST-segment elevation (NSTSE) acute coronary syndrome (ACS), according to Spanish researchers.
纽约（路透社健康报）12月28日文-西班牙研究者发现功能性二尖瓣返流的恶化和非-ST段抬高的急性冠脉综合症患者心搏量的减少是相关的。
In the November issue of the European Heart Journal, Dr. Leopoldo Perez de Isla and colleagues point out that although the development of MR after myocardial infarction is a frequent complication that has a negative impact on survival. However, relatively little is known about the effect of MR in NSTSEACS patients.
在欧洲心脏杂志11月份刊中，Leopoldo Perez de Isla博士和合作者指出心肌梗死后出现的二尖瓣返流是一个常见的并发症而且不影响生存率。然而，二尖瓣返流对非-ST段抬高的急性冠脉综合症患者的影响了解甚少。
To investigate further, the researchers followed 300 such patients admitted to the coronary care unit of their institution, Hospital Clinico San Carlos, Madrid.
为了进一步的观察，研究者随访了马德里，圣罗卡斯临床医院冠心病监护室（CCU)的300名患者。
In 42% of the group, MR was detected. Age and left ventricular ejection fraction were the only predictors of its development. There was no independent predictor of in-hospital mortality, although such mortality was significantly higher in the MR group than the non-MR group.
有42%的患者被检测到有二尖瓣返流，年龄和左心室射血分数是评价二尖瓣发展的唯一指标。没有一个独立的指标来评价医院死亡率，虽然在二尖瓣返流病人中医院死亡率要显著的高于无二尖瓣返流的病人。
Follow-up for a mean of more than 14 months, showed that long-term outcome was dependent on MR severity. Moreover, this was the sole independent predictor of poor long term prognosis.
在进行超过14个月的随访发现：二尖瓣返流的严重性决定了远期的结果。而且，这还是一个远期预后不好的独立指标。
Dr. Perez de Isla told Reuters Health that because of these findings, "the presence of mitral regurgitation should be specifically assessed in every patient in this scenario."
Perez de Isla博士接受路透社健康报采访时说：因为他们的这些发现，“每一个病人的治疗方案中应该在明确评定二尖瓣返流的存在。”
In an accompanying editorial, Dr. Luc A. Pierard of University Hospital Sart Tilman, Liege, Belgium agrees and notes that MR should be identified in a variety of cardiac patients.
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作者:admin@医学,生命科学 2011-03-15 17:11
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