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Antiacid supplement boosts bone mass
"Our results demonstrate for the first time that merely by partially reversing the acidity of the diet, bone mass increased rapidly and in amounts that are within the range of increase produced by common FDA-approved medicines," Dr. Reto Krapf, from the University of Basel in Switzerland, said in a statement.
The effect of continuously high acid levels on bone formation is controversial, but there is some evidence to suggest that they are associated with a drop in bone mineral density. Thus, neutralizing high acidity might increase bone mass.
The current study, described in the Journal of the American Society of Nephrology, involved 161 women with subpar bone mineral density who were randomly assigned to take potassium citrate, a base compound that reacts with acid to neutralize it, or potassium chloride daily for six to 12 months.
The women taking potassium citrate showed significant increases in BMD at the spine and hip compared with the women given potassium chloride.
Further studies examining the effects on fracture rates are needed before potassium citrate can be widely recommended as a treatment for osteoporosis, Krapf noted. "However, given the safety and extremely low cost of this agent, these results should be very encouraging to government agencies regarding funding for future trials," he added.
Last Updated: 2006-10-20 9:35:51 -0400 (Reuters Health) 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 Antiacid supplement boosts bone mass
抗酸剂添加物能提高骨量
NEW YORK (Reuters Health), Oct 20 - Taking potassium citrate, a base, to neutralize the high acidity of typical Western diets can help increase bone mass in postmenopausal women with thinning bones, according to researchers in Switzerland and San Francisco.
"Our results demonstrate for the first time that merely by partially reversing the acidity of the diet, bone mass increased rapidly and in amounts that are within the range of increase produced by common FDA-approved medicines," Dr. Reto Krapf, from the University of Basel in Switzerland, said in a statement.
纽约（路透通讯社健康专栏），10月20日—据瑞士及旧金山的研究者报道，服用枸橼酸钾作为一种基础成分，可中和典型西方饮食的高酸度，并帮助增加经绝后骨质疏松女性的骨量。
The effect of continuously high acid levels on bone formation is controversial, but there is some evidence to suggest that they are associated with a drop in bone mineral density. Thus, neutralizing high acidity might increase bone mass.
持续高酸水平对于骨形成的影响众说不一，但有证据提示它们与骨矿物质密度的下降相关。因此，中和高酸度可能提高骨量。
The current study, described in the Journal of the American Society of Nephrology, involved 161 women with subpar bone mineral density who were randomly assigned to take potassium citrate, a base compound that reacts with acid to neutralize it, or potassium chloride daily for six to 12 months.
美国肾病学会杂志描述，目前的研究包括骨矿物质密度在平均水平以下的161位女性，随机指定服用枸橼酸钾为基础成分的混合物，与酸反应并将其中和，或6~12个月每天服用氯化钾。
The women taking potassium citrate showed significant increases in BMD at the spine and hip compared with the women given potassium chloride.
与服用氯化钾的女性相比，服用枸橼酸钾的女性的脊骨及髋骨表现骨矿物质密度明显升高。
Further studies examining the effects on fracture rates are needed before potassium citrate can be widely recommended as a treatment for osteoporosis, Krapf noted. "However, given the safety and extremely low cost of this agent, these results should be very encouraging to government agencies regarding funding for future trials," he added.
Krapf注意到，在枸橼酸钾被广泛推荐应用于骨质酥松的治疗前，需要进一步研究其对于骨折比率的作用。“无论如何，考虑到此药物的安全性及相当低廉的成本，这些结果应该能鼓励政府机构提供未来研究的相关资金。”
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作者:admin@医学,生命科学 2010-10-14 05:11
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